2,6-Dichloroquinone-4-chloroimide
Based on 1 Customer Validation
2,6-Dichloroquinone-4-chloroimide is a spray reagent for organic compounds. 2,6-Dichloroquinone-4-chloroimide can be used in thin-layer chromatograms and detecting phenol and its derivatives. 2,6-Dichloroquinone-4-chloroimide can be used as an optical sensor for rapid detection of permethrin in treated wood.
For research use only. We do not sell to patients.
- Purity: 99.13%
- CAS No.: 101-38-2
- Formula: C6H2Cl3NO
- Molecular Weight:210.45
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
2,6-Dichloroquinone-4-chloroimide is a biochemical reagent that can be used as a detection reagent or optical sensor in life science related research.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 101-38-2
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Appearance Solid
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Molecular Weight 210.45
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Formula C6H2Cl3NO
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Color Light yellow to brown
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SMILES
C1=C(C(=O)C(=CC1=NCl)Cl)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (475.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (11.88 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (275 KB)
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SDS (545 KB)
- English - EN (545 KB)
- Français - FR (545 KB)
- Deutsch - DE (545 KB)
- Norwegian - NO (545 KB)
- Español - ES (545 KB)
- Swedish - SV (545 KB)
- Italian - IT (545 KB)
- Korean - KR (545 KB)
- Portuguese - PT (545 KB)
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Handling Instructions (2659 KB)
References
[2]. Arip MN, et al. Reaction of 2,6-dichloroquinone-4-chloroimide (Gibbs reagent) with permethrin - an optical sensor for rapid detection of permethrin in treated wood. Chem Cent J. 2013 Jul 16;7:122. [Content Brief]
[3]. Xu S, et al. Haloquinone Chloroimides as Toxic Disinfection Byproducts Identified in Drinking Water. Environ Sci Technol. 2021 Dec 21;55(24):16347-16357. [Content Brief]
[5]. Andrew J Fratoni, et al. Imipenem/funobactam (formerly XNW4107) in vivo pharmacodynamics against serine carbapenemase-producing Gram-negative bacteria: a novel modelling approach for time-dependent killing. J Antimicrob Chemother. 2023 Sep 5;78(9):2343-2353. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7517 mL | 23.7586 mL | 47.5172 mL | 118.7931 mL |
| 5 mM | 0.9503 mL | 4.7517 mL | 9.5034 mL | 23.7586 mL | |
| 10 mM | 0.4752 mL | 2.3759 mL | 4.7517 mL | 11.8793 mL | |
| 15 mM | 0.3168 mL | 1.5839 mL | 3.1678 mL | 7.9195 mL | |
| 20 mM | 0.2376 mL | 1.1879 mL | 2.3759 mL | 5.9397 mL | |
| 25 mM | 0.1901 mL | 0.9503 mL | 1.9007 mL | 4.7517 mL | |
| 30 mM | 0.1584 mL | 0.7920 mL | 1.5839 mL | 3.9598 mL | |
| 40 mM | 0.1188 mL | 0.5940 mL | 1.1879 mL | 2.9698 mL | |
| 50 mM | 0.0950 mL | 0.4752 mL | 0.9503 mL | 2.3759 mL | |
| 60 mM | 0.0792 mL | 0.3960 mL | 0.7920 mL | 1.9799 mL | |
| 80 mM | 0.0594 mL | 0.2970 mL | 0.5940 mL | 1.4849 mL | |
| 100 mM | 0.0475 mL | 0.2376 mL | 0.4752 mL | 1.1879 mL |
2,6-Dichloroquinone-4-chloroimide Related Classifications
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