2,6-Dichloroquinone-4-chloroimide

Name: 2,6-Dichloroquinone-4-chloroimide
Brand: MedChemExpress
SKU: HY-W105135
Rating: 4.5 (1 reviews)

Cat. No.: HY-W105135 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

2,6-Dichloroquinone-4-chloroimide is a spray reagent for organic compounds. 2,6-Dichloroquinone-4-chloroimide can be used in thin-layer chromatograms. 2,6-Dichloroquinone-4-chloroimide can be used as an optical sensor for rapid detection of permethrin in treated wood.

For research use only. We do not sell to patients.

2,6-Dichloroquinone-4-chloroimide Chemical Structure

CAS No. : 101-38-2

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
50 mg	USD 32	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 95	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

210.45

Formula

C₆H₂Cl₃NO

CAS No.

101-38-2

Appearance

Solid

Color

Light yellow to brown

SMILES

C1=C(C(=O)C(=CC1=NCl)Cl)Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (475.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.7517 mL	23.7586 mL	47.5172 mL
5 mM	0.9503 mL	4.7517 mL	9.5034 mL
10 mM	0.4752 mL	2.3759 mL	4.7517 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (11.88 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (273 KB) SDS (0 KB)

COA (251 KB) HNMR (165 KB)

Handling Instructions (2659 KB)

References

[1]. Joseph H. Ross, et al. 2,6-Dichloroquinone 4-chloroimide as a reagent for amines and aromatic hydrocarbons on thin-layer chromatograms. Anal. Chem. 1968, 40, 14, 2138–2143.

[2]. Arip MN, et al. Reaction of 2,6-dichloroquinone-4-chloroimide (Gibbs reagent) with permethrin - an optical sensor for rapid detection of permethrin in treated wood. Chem Cent J. 2013 Jul 16;7:122. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.7517 mL	23.7586 mL	47.5172 mL	118.7931 mL
	5 mM	0.9503 mL	4.7517 mL	9.5034 mL	23.7586 mL
	10 mM	0.4752 mL	2.3759 mL	4.7517 mL	11.8793 mL
	15 mM	0.3168 mL	1.5839 mL	3.1678 mL	7.9195 mL
	20 mM	0.2376 mL	1.1879 mL	2.3759 mL	5.9397 mL
	25 mM	0.1901 mL	0.9503 mL	1.9007 mL	4.7517 mL
	30 mM	0.1584 mL	0.7920 mL	1.5839 mL	3.9598 mL
	40 mM	0.1188 mL	0.5940 mL	1.1879 mL	2.9698 mL
	50 mM	0.0950 mL	0.4752 mL	0.9503 mL	2.3759 mL
	60 mM	0.0792 mL	0.3960 mL	0.7920 mL	1.9799 mL
	80 mM	0.0594 mL	0.2970 mL	0.5940 mL	1.4849 mL
	100 mM	0.0475 mL	0.2376 mL	0.4752 mL	1.1879 mL