2-(Aminooxy)ethanamine dihydrochloride
Based on 1 Customer Validation
2-(Aminooxy)ethanamine (dihydrochloride) is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 97.88%
- CAS No.: 37866-45-8
- Formula: C2H10Cl2N2O
- Molecular Weight:149.02
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E204 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 37866-45-8
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Appearance Solid
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Molecular Weight 149.02
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Formula C2H10Cl2N2O
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Color White to off-white
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SMILES
NOCCN.Cl.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (167.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (241 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.7105 mL | 33.5525 mL | 67.1051 mL | 167.7627 mL |
| 5 mM | 1.3421 mL | 6.7105 mL | 13.4210 mL | 33.5525 mL | |
| 10 mM | 0.6711 mL | 3.3553 mL | 6.7105 mL | 16.7763 mL | |
| 15 mM | 0.4474 mL | 2.2368 mL | 4.4737 mL | 11.1842 mL | |
| 20 mM | 0.3355 mL | 1.6776 mL | 3.3553 mL | 8.3881 mL | |
| 25 mM | 0.2684 mL | 1.3421 mL | 2.6842 mL | 6.7105 mL | |
| 30 mM | 0.2237 mL | 1.1184 mL | 2.2368 mL | 5.5921 mL | |
| 40 mM | 0.1678 mL | 0.8388 mL | 1.6776 mL | 4.1941 mL | |
| 50 mM | 0.1342 mL | 0.6711 mL | 1.3421 mL | 3.3553 mL | |
| 60 mM | 0.1118 mL | 0.5592 mL | 1.1184 mL | 2.7960 mL | |
| 80 mM | 0.0839 mL | 0.4194 mL | 0.8388 mL | 2.0970 mL | |
| 100 mM | 0.0671 mL | 0.3355 mL | 0.6711 mL | 1.6776 mL |