2-(Aminooxy)ethanamine dihydrochloride

Cat. No.: HY-78768 Pureza: ≥95.0%: Ficha de datos
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2-(Aminooxy)ethanamine (dihydrochloride) is a PROTAC linker that can be used in the synthesis of PROTACs.

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2-(Aminooxy)ethanamine dihydrochloride Estructura química

No. CAS : 37866-45-8

Tamaño	Stock	Cantidad
100 mg	En stock	Estimated Time of Arrival: December 31
500 mg	En stock	Estimated Time of Arrival: December 31
1 g	Obtener un presupuesto
5 g	Obtener un presupuesto

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Descripciòn

2-(Aminooxy)ethanamine (dihydrochloride) is a PROTAC linker that can be used in the synthesis of PROTACs.

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E204 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

149.02

Fòrmula

C₂H₁₀Cl₂N₂O

No. CAS

37866-45-8

Appearance

Solid

Color

White to off-white

SMILES

NOCCN.Cl.Cl

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvente y solubilidad

In Vitro:

DMSO : 25 mg/mL (167.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.7105 mL	33.5525 mL	67.1051 mL
5 mM	1.3421 mL	6.7105 mL	13.4210 mL
10 mM	0.6711 mL	3.3553 mL	6.7105 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureza y Documentación

Purity: ≥98.0%

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Ficha de datos (241 KB) SDS (396 KB)

COA (244 KB) HNMR (124 KB)

Instrucciones de manejo (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.7105 mL	33.5525 mL	67.1051 mL	167.7627 mL
	5 mM	1.3421 mL	6.7105 mL	13.4210 mL	33.5525 mL
	10 mM	0.6711 mL	3.3553 mL	6.7105 mL	16.7763 mL
	15 mM	0.4474 mL	2.2368 mL	4.4737 mL	11.1842 mL
	20 mM	0.3355 mL	1.6776 mL	3.3553 mL	8.3881 mL
	25 mM	0.2684 mL	1.3421 mL	2.6842 mL	6.7105 mL
	30 mM	0.2237 mL	1.1184 mL	2.2368 mL	5.5921 mL
	40 mM	0.1678 mL	0.8388 mL	1.6776 mL	4.1941 mL
	50 mM	0.1342 mL	0.6711 mL	1.3421 mL	3.3553 mL
	60 mM	0.1118 mL	0.5592 mL	1.1184 mL	2.7960 mL
	80 mM	0.0839 mL	0.4194 mL	0.8388 mL	2.0970 mL
	100 mM	0.0671 mL	0.3355 mL	0.6711 mL	1.6776 mL