2'-Deoxy-2'-fluoroarabino inosine
Based on 1 Customer Validation
2’-Deoxy-2’-fluoroarabino inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 98983-40-5
- Formula: C10H11FN4O4
- Molecular Weight:270.22
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
>100 μM
Compound: 15
|
The cytotoxicity against CEM cells
The cytotoxicity against CEM cells
|
[PMID: 9276020] |
| HepG2 | EC50 |
8 μM
Compound: 15
|
compound was tested in vitro for anti HBV activity in HepG2 2.2.15 cells
compound was tested in vitro for anti HBV activity in HepG2 2.2.15 cells
|
[PMID: 9276020] |
| HepG2 | IC50 |
>200 μM
Compound: 15
|
The cytotoxicity against 2.2.15 cells expressed as IC50
The cytotoxicity against 2.2.15 cells expressed as IC50
|
[PMID: 9276020] |
Chemical Information
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CAS No. 98983-40-5
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Appearance Solid
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Molecular Weight 270.22
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Formula C10H11FN4O4
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Color White to off-white
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SMILES
O[C@H]1[C@H](F)[C@H](N(C=N2)C3=C2C(NC=N3)=O)O[C@@H]1CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)