1. 天然物
  2. Plants Flavonoids
  3. Selaginellaceae Biflavones
  4. Selaginella doederleinii Hieron.
  5. (2"S)-6"-Methyl-2",3"-Dihydrodelicaflavone

(2"S)-6"-Methyl-2",3"-Dihydrodelicaflavone 

製品番号: HY-N18316
取扱説明書 Technical Support

(2''S)-6''-Methyl-2'',3''-Dihydrodelicaflavone is a biflavonoid compound present in the whole herb of Selaginella doederleinii. (2''S)-6''-Methyl-2'',3''-Dihydrodelicaflavone exhibits antiproliferative activity against non-small cell lung cancer cells (IC50 = 3.1-6.8 μM) with low cytotoxicity toward normal cells. (2''S)-6''-Methyl-2'',3''-Dihydrodelicaflavone can be used in studies related to non-small cell lung cancer.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

(2

(2"S)-6"-Methyl-2",3"-Dihydrodelicaflavone 構造式

CAS 番号 : 3035699-20-5

容量 在庫状況
50 mg   お問い合わせ  
100 mg   お問い合わせ  
250 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

Top Publications Citing Use of Products
  • 生物活性

  • 純度とドキュメンテーション

  • 参考文献

  • カスタマーレビュー

製品説明

(2''S)-6''-Methyl-2'',3''-Dihydrodelicaflavone is a biflavonoid compound present in the whole herb of Selaginella doederleinii. (2''S)-6''-Methyl-2'',3''-Dihydrodelicaflavone exhibits antiproliferative activity against non-small cell lung cancer cells (IC50 = 3.1-6.8 μM) with low cytotoxicity toward normal cells. (2''S)-6''-Methyl-2'',3''-Dihydrodelicaflavone can be used in studies related to non-small cell lung cancer[1].

体外実験

(2''S)-6''-Methyl-2'',3''-Dihydrodelicaflavone (compound 4) (0-100 μM; 24 h) potently inhibits the proliferation of A549 and H1299 non-small cell lung cancer cells in vitro, and exhibits low cytotoxicity against normal MRC-5 lung cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: human non-small cell lung cancer A549 cells, human non-small cell lung cancer H1299 cells, human normal embryonic lung MRC-5 cells
Concentration: 0-100 μM
Incubation Time: 24 h
Result: Potently inhibited proliferation of A549 cells with an IC50 of 3.1 μM.
Inhibited proliferation of H1299 cells with an IC50 of 6.8 μM.
Showed low toxicity to non-cancer MRC-5 cells with an IC50 of 58.2 μM.
分子量

554.50

分子式

C31H22O10

CAS 番号
SMILES

O=C(C(OC1=CC=C([C@H]2OC3=CC(O)=C(C)C(O)=C3C(C2)=O)C=C1)=C(C4=CC=C(C=C4)O)OC5=CC(O)=C6)C5=C6O

Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション
参考文献
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

最近チェックした製品:

オンラインお問い合わせ

Your information is safe with us. * Required Fields.

製品名

 

カスタマ需要量 *

お名前 *

 

タイトル

メールアドレス *

 

電話番号 *

デパートメント

 

組纖名 *

市区町村

都道府県

国或いは地域 *

     

必ず会社名を記載ください。個人への返信は行いません。

備考

バルクお問い合わせ

Inquiry Information

製品名:
(2"S)-6"-Methyl-2",3"-Dihydrodelicaflavone
製品番号:
HY-N18316
数量:
MCE 日本正規代理店: