3-Boc-aminoethylazetidine hydrochlordie
Based on 1 Customer Validation
3-Boc-aminoethylazetidine hydrochlordie is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥98.0%
- CAS No.: 1170905-43-7
- Formula: C10H21ClN2O2
- Molecular Weight:236.74
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E299 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1170905-43-7
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Appearance Solid
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Molecular Weight 236.74
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Formula C10H21ClN2O2
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Color White to off-white
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SMILES
Cl.O=C(OC(C)(C)C)NCCC1CNC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (422.40 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2240 mL | 21.1202 mL | 42.2404 mL | 105.6011 mL |
| 5 mM | 0.8448 mL | 4.2240 mL | 8.4481 mL | 21.1202 mL | |
| 10 mM | 0.4224 mL | 2.1120 mL | 4.2240 mL | 10.5601 mL | |
| 15 mM | 0.2816 mL | 1.4080 mL | 2.8160 mL | 7.0401 mL | |
| 20 mM | 0.2112 mL | 1.0560 mL | 2.1120 mL | 5.2801 mL | |
| 25 mM | 0.1690 mL | 0.8448 mL | 1.6896 mL | 4.2240 mL | |
| 30 mM | 0.1408 mL | 0.7040 mL | 1.4080 mL | 3.5200 mL | |
| 40 mM | 0.1056 mL | 0.5280 mL | 1.0560 mL | 2.6400 mL | |
| 50 mM | 0.0845 mL | 0.4224 mL | 0.8448 mL | 2.1120 mL | |
| 60 mM | 0.0704 mL | 0.3520 mL | 0.7040 mL | 1.7600 mL | |
| 80 mM | 0.0528 mL | 0.2640 mL | 0.5280 mL | 1.3200 mL | |
| 100 mM | 0.0422 mL | 0.2112 mL | 0.4224 mL | 1.0560 mL |