3-Butyn-1-amine hydrochloride
Based on 1 Customer Validation
3-Butyn-1-amine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥98.0%
- CAS No.: 88211-50-1
- Formula: C4H8ClN
- Molecular Weight:105.57
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E303 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 88211-50-1
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Appearance Solid
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Molecular Weight 105.57
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Formula C4H8ClN
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Color White to off-white
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SMILES
Cl.C#CCCN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (947.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (241 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 9.4724 mL | 47.3619 mL | 94.7239 mL | 236.8097 mL |
| 5 mM | 1.8945 mL | 9.4724 mL | 18.9448 mL | 47.3619 mL | |
| 10 mM | 0.9472 mL | 4.7362 mL | 9.4724 mL | 23.6810 mL | |
| 15 mM | 0.6315 mL | 3.1575 mL | 6.3149 mL | 15.7873 mL | |
| 20 mM | 0.4736 mL | 2.3681 mL | 4.7362 mL | 11.8405 mL | |
| 25 mM | 0.3789 mL | 1.8945 mL | 3.7890 mL | 9.4724 mL | |
| 30 mM | 0.3157 mL | 1.5787 mL | 3.1575 mL | 7.8937 mL | |
| 40 mM | 0.2368 mL | 1.1840 mL | 2.3681 mL | 5.9202 mL | |
| 50 mM | 0.1894 mL | 0.9472 mL | 1.8945 mL | 4.7362 mL | |
| 60 mM | 0.1579 mL | 0.7894 mL | 1.5787 mL | 3.9468 mL | |
| 80 mM | 0.1184 mL | 0.5920 mL | 1.1840 mL | 2.9601 mL | |
| 100 mM | 0.0947 mL | 0.4736 mL | 0.9472 mL | 2.3681 mL |
3-Butyn-1-amine hydrochloride Related Classifications
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