3’-Deoxy-3’-fluoro-xylocytidine
3’-Deoxy-3’-fluoro-xylocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- CAS No.: 26563-01-9
- Formula: C9H12FN3O4
- Molecular Weight:245.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
39 μg/mL
Compound: 25
|
Concentration required to reduce the viability of Murine leukemia L1210 cells
Concentration required to reduce the viability of Murine leukemia L1210 cells
|
[PMID: 2066992] |
| MOLT-4F | IC50 |
65 μg/mL
Compound: 25
|
Concentration required to reduce the viability of Human T-lymphoblast Molt/4F cells
Concentration required to reduce the viability of Human T-lymphoblast Molt/4F cells
|
[PMID: 2066992] |
| MT4 | IC50 |
7.9 μg/mL
Compound: 25
|
Concentration required to reduce the viability of Human T-lymphoblast MT-4 cells
Concentration required to reduce the viability of Human T-lymphoblast MT-4 cells
|
[PMID: 2066992] |
| Raji | IC50 |
98 μg/mL
Compound: 25
|
Concentration required to reduce the viability of Human B-lymphoblast Raji cells
Concentration required to reduce the viability of Human B-lymphoblast Raji cells
|
[PMID: 2066992] |
Chemical Information
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CAS No. 26563-01-9
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Molecular Weight 245.21
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Formula C9H12FN3O4
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SMILES
OC[C@@H]1[C@H](F)[C@@H](O)[C@H](N2C=CC(N)=NC2=O)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)