2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 3’-Deoxy-3’-fluoro-xylocytidine

3’-Deoxy-3’-fluoro-xylocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

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3’-Deoxy-3’-fluoro-xylocytidine

3’-Deoxy-3’-fluoro-xylocytidine Estructura química

No. CAS : 26563-01-9

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3’-Deoxy-3’-fluoro-xylocytidine Related Antibodies

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Descripciòn

3’-Deoxy-3’-fluoro-xylocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cellular Effect
Cell Line Type Value Description References
L1210 IC50
39 μg/mL
Compound: 25
Concentration required to reduce the viability of Murine leukemia L1210 cells
Concentration required to reduce the viability of Murine leukemia L1210 cells
[PMID: 2066992]
MOLT-4F IC50
65 μg/mL
Compound: 25
Concentration required to reduce the viability of Human T-lymphoblast Molt/4F cells
Concentration required to reduce the viability of Human T-lymphoblast Molt/4F cells
[PMID: 2066992]
MT4 IC50
7.9 μg/mL
Compound: 25
Concentration required to reduce the viability of Human T-lymphoblast MT-4 cells
Concentration required to reduce the viability of Human T-lymphoblast MT-4 cells
[PMID: 2066992]
Raji IC50
98 μg/mL
Compound: 25
Concentration required to reduce the viability of Human B-lymphoblast Raji cells
Concentration required to reduce the viability of Human B-lymphoblast Raji cells
[PMID: 2066992]
Peso molecular

245.21

Fòrmula

C9H12FN3O4
No. CAS
SMILES

OC[C@@H]1[C@H](F)[C@@H](O)[C@H](N2C=CC(N)=NC2=O)O1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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3’-Deoxy-3’-fluoro-xylocytidine Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3’-Deoxy-3’-fluoro-xylocytidine26563-01-9Nucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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Nombre del producto:
3’-Deoxy-3’-fluoro-xylocytidine
Cat. No.:
HY-152759
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