3’-Deoxy-3’-fluoroinosine
3’-Deoxy-3’-fluoroinosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- CAS No.: 117517-20-1
- Formula: C10H11FN4O4
- Molecular Weight:270.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Macrophage | EC50 |
>64 μM
Compound: 5
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Cytotoxicity against mouse primary macrophage cells assessed as reduction in cell viability
Cytotoxicity against mouse primary macrophage cells assessed as reduction in cell viability
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[PMID: 33667845] |
| MRC5 | EC50 |
>64 μM
Compound: 5
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Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 3 days by resazurin dye based fluorimetric analysis
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 3 days by resazurin dye based fluorimetric analysis
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[PMID: 33667845] |
Chemical Information
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CAS No. 117517-20-1
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Molecular Weight 270.22
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Formula C10H11FN4O4
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SMILES
OC[C@@H]1[C@@H](F)[C@@H](O)[C@H](N(C=N2)C3=C2C(NC=N3)=O)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3’-Deoxy-3’-fluoroinosine Related Classifications
HY-152730 Related Classifications
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