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Cat. No.: HY-N13736

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3-epi-Dihydroscandenolide

(Synonyms: 3β-Acetoxy-1,10-epoxy-4-germacrene-12,8; 15,6-diolide)

3-epi-Dihydroscandenolide (3β-Acetoxy-1,10-epoxy-4-germacrene-12,8; 15,6-diolide) is a sesquiterpene lactone inhibitor of influenza A virus. 3-epi-Dihydroscandenolide can be isolated from the dried aerial parts of Mikania micrantha. 3-epi-Dihydroscandenolide inhibits the cytopathic effect induced by influenza A virus and can be used in studies related to influenza A.

For research use only. We do not sell to patients.

CAS No.: 1137951-08-6
Formula: C₁₇H₂₀O₇
Molecular Weight:336.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

3-epi-Dihydroscandenolide Chemical Structure

CAS No.: 1137951-08-6

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HEp-2	IC₅₀	186.3 μM Compound: 1	Antiviral activity against Parainfluenza virus type 3 infected in human Hep2 cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay Antiviral activity against Parainfluenza virus type 3 infected in human Hep2 cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay	[PMID: 19267453]
HEp-2	IC₅₀	61.9 μM Compound: 1	Antiviral activity against Respiratory syncytial virus infected in human Hep2 cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay Antiviral activity against Respiratory syncytial virus infected in human Hep2 cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay	[PMID: 19267453]
MDCK	IC₅₀	186 μM Compound: 1	Antiviral activity against Influenza A virus infected in MDCK cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay Antiviral activity against Influenza A virus infected in MDCK cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay	[PMID: 19267453]

Chemical Information

CAS No. 1137951-08-6
Molecular Weight 336.34
Formula C₁₇H₂₀O₇
SMILES

C[C@]12[C@@](C[C@@H](C3=C[C@](OC3=O)([H])[C@@]4([H])[C@](OC([C@@H]4C)=O)([H])C2)OC(C)=O)([H])O1
Synonyms

3β-Acetoxy-1,10-epoxy-4-germacrene-12,8; 15,6-diolide
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. But PP, et al. Antiviral constituents against respiratory viruses from Mikania micrantha. J Nat Prod. 2009;72(5):925-928. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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