3-(Piperidin-4-yl)propan-1-ol
Based on 1 Customer Validation
3-(Piperidin-4-yl)propan-1-ol is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- CAS No.: 7037-49-2
- Formula: C8H17NO
- Molecular Weight:143.23
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E282 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 7037-49-2
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Appearance Solid
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Molecular Weight 143.23
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Formula C8H17NO
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SMILES
OCCCC1CCNCC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (698.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (239 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.9818 mL | 34.9089 mL | 69.8178 mL | 174.5444 mL |
| 5 mM | 1.3964 mL | 6.9818 mL | 13.9636 mL | 34.9089 mL | |
| 10 mM | 0.6982 mL | 3.4909 mL | 6.9818 mL | 17.4544 mL | |
| 15 mM | 0.4655 mL | 2.3273 mL | 4.6545 mL | 11.6363 mL | |
| 20 mM | 0.3491 mL | 1.7454 mL | 3.4909 mL | 8.7272 mL | |
| 25 mM | 0.2793 mL | 1.3964 mL | 2.7927 mL | 6.9818 mL | |
| 30 mM | 0.2327 mL | 1.1636 mL | 2.3273 mL | 5.8181 mL | |
| 40 mM | 0.1745 mL | 0.8727 mL | 1.7454 mL | 4.3636 mL | |
| 50 mM | 0.1396 mL | 0.6982 mL | 1.3964 mL | 3.4909 mL | |
| 60 mM | 0.1164 mL | 0.5818 mL | 1.1636 mL | 2.9091 mL | |
| 80 mM | 0.0873 mL | 0.4364 mL | 0.8727 mL | 2.1818 mL | |
| 100 mM | 0.0698 mL | 0.3491 mL | 0.6982 mL | 1.7454 mL |