(3S)Lenalidomide-5-methylpiperazine benzenesulfonate
Based on 1 Customer Validation
(3S)Lenalidomide-5-methylpiperazine benzenesulfonate is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
For research use only. We do not sell to patients.
- Purity: ≥95.0%
- CAS No.: 2229714-16-1
- Formula: C23H26N4O6S
- Molecular Weight:486.54
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2229714-16-1
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Appearance Solid
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Molecular Weight 486.54
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Formula C23H26N4O6S
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Color White to off-white
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SMILES
S(=O)(=O)(O)C1=CC=CC=C1.O=C1N(CC=2C1=CC=C(C2)N3CCNCC3)[C@@H]4C(=O)NC(=O)CC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (102.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (242 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0553 mL | 10.2766 mL | 20.5533 mL | 51.3832 mL |
| 5 mM | 0.4111 mL | 2.0553 mL | 4.1107 mL | 10.2766 mL | |
| 10 mM | 0.2055 mL | 1.0277 mL | 2.0553 mL | 5.1383 mL | |
| 15 mM | 0.1370 mL | 0.6851 mL | 1.3702 mL | 3.4255 mL | |
| 20 mM | 0.1028 mL | 0.5138 mL | 1.0277 mL | 2.5692 mL | |
| 25 mM | 0.0822 mL | 0.4111 mL | 0.8221 mL | 2.0553 mL | |
| 30 mM | 0.0685 mL | 0.3426 mL | 0.6851 mL | 1.7128 mL | |
| 40 mM | 0.0514 mL | 0.2569 mL | 0.5138 mL | 1.2846 mL | |
| 50 mM | 0.0411 mL | 0.2055 mL | 0.4111 mL | 1.0277 mL | |
| 60 mM | 0.0343 mL | 0.1713 mL | 0.3426 mL | 0.8564 mL | |
| 80 mM | 0.0257 mL | 0.1285 mL | 0.2569 mL | 0.6423 mL | |
| 100 mM | 0.0206 mL | 0.1028 mL | 0.2055 mL | 0.5138 mL |
(3S)Lenalidomide-5-methylpiperazine benzenesulfonate Related Classifications
HY-46011 Related Classifications
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