2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. (3S)Lenalidomide-5-methylpiperazine benzenesulfonate

(3S)Lenalidomide-5-methylpiperazine benzenesulfonate 

Cat. No.: HY-46011 Purity: ≥95.0%
COA
SDS
Handling Instructions Technical Support

(3S)Lenalidomide-5-methylpiperazine benzenesulfonate is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

(3S)Lenalidomide-5-methylpiperazine benzenesulfonate

(3S)Lenalidomide-5-methylpiperazine benzenesulfonate 화학구조

CAS No. : 2229714-16-1

사이즈 가격 재고 수량
100 mg 해외재고보유
250 mg 해외재고보유
500 mg 해외재고보유
1 g 해외재고보유
5 g   견적 받기  
10 g   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

Other Forms of (3S)Lenalidomide-5-methylpiperazine benzenesulfonate:

(3S)Lenalidomide-5-methylpiperazine benzenesulfonate Related Antibodies

Top Publications Citing Use of Products

View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

  • Biological Activity

  • 순도&문서

  • 고객리뷰

제품 설명

(3S)Lenalidomide-5-methylpiperazine benzenesulfonate is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

IC50 & Target

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(3S)Lenalidomide-5-methylpiperazine benzenesulfonate Related Antibodies
분자량

486.54

화학식

C23H26N4O6S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

S(=O)(=O)(O)C1=CC=CC=C1.O=C1N(CC=2C1=CC=C(C2)N3CCNCC3)[C@@H]4C(=O)NC(=O)CC4
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

순도&문서

Purity: ≥97.0%

SDS (393 KB)

COA (247 KB) HNMR (135 KB) LCMS (89 KB)

Handling Instructions (2659 KB)
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(3S)Lenalidomide-5-methylpiperazine benzenesulfonate Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(3S)Lenalidomide-5-methylpiperazine2229714-16-1E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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상품명:
(3S)Lenalidomide-5-methylpiperazine benzenesulfonate
Cat. No.:
HY-46011
수량:
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SAFETY DATA SHEET (SDS)

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