4-(1-Boc-4-piperidyl)phenylboronic acid pinacol ester
Based on 1 Customer Validation
4-(1-Boc-4-piperidyl)phenylboronic acid pinacol ester is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥98.0%
- CAS No.: 956136-85-9
- Formula: C22H34BNO4
- Molecular Weight:387.33
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E326 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 956136-85-9
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Appearance Solid
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Molecular Weight 387.33
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Formula C22H34BNO4
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Color White to off-white
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SMILES
O=C(OC(C)(C)C)N1CCC(C2=CC=C(C=C2)B3OC(C)(C)C(O3)(C)C)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (64.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (242 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5818 mL | 12.9089 mL | 25.8178 mL | 64.5444 mL |
| 5 mM | 0.5164 mL | 2.5818 mL | 5.1636 mL | 12.9089 mL | |
| 10 mM | 0.2582 mL | 1.2909 mL | 2.5818 mL | 6.4544 mL | |
| 15 mM | 0.1721 mL | 0.8606 mL | 1.7212 mL | 4.3030 mL | |
| 20 mM | 0.1291 mL | 0.6454 mL | 1.2909 mL | 3.2272 mL | |
| 25 mM | 0.1033 mL | 0.5164 mL | 1.0327 mL | 2.5818 mL | |
| 30 mM | 0.0861 mL | 0.4303 mL | 0.8606 mL | 2.1515 mL | |
| 40 mM | 0.0645 mL | 0.3227 mL | 0.6454 mL | 1.6136 mL | |
| 50 mM | 0.0516 mL | 0.2582 mL | 0.5164 mL | 1.2909 mL | |
| 60 mM | 0.0430 mL | 0.2151 mL | 0.4303 mL | 1.0757 mL |
4-(1-Boc-4-piperidyl)phenylboronic acid pinacol ester Related Classifications
HY-W024904 Related Classifications
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