4-(2-Boc-aminoethyl)piperidine
Based on 1 Customer Validation
4-(2-Boc-aminoethyl)piperidine is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: ≥95.0%
- CAS No.: 165528-81-4
- Formula: C12H24N2O2
- Molecular Weight:228.34
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
![[Bmpip][NTf2]](https://file.medchemexpress.com/product_pic/hy-w127701.gif)
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E330 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 165528-81-4
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Appearance Solid-Liquid Mixture
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Molecular Weight 228.34
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Formula C12H24N2O2
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Color Colorless to off-white
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SMILES
O=C(OC(C)(C)C)NCCC1CCNCC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (109.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3794 mL | 21.8972 mL | 43.7943 mL | 109.4859 mL |
| 5 mM | 0.8759 mL | 4.3794 mL | 8.7589 mL | 21.8972 mL | |
| 10 mM | 0.4379 mL | 2.1897 mL | 4.3794 mL | 10.9486 mL | |
| 15 mM | 0.2920 mL | 1.4598 mL | 2.9196 mL | 7.2991 mL | |
| 20 mM | 0.2190 mL | 1.0949 mL | 2.1897 mL | 5.4743 mL | |
| 25 mM | 0.1752 mL | 0.8759 mL | 1.7518 mL | 4.3794 mL | |
| 30 mM | 0.1460 mL | 0.7299 mL | 1.4598 mL | 3.6495 mL | |
| 40 mM | 0.1095 mL | 0.5474 mL | 1.0949 mL | 2.7371 mL | |
| 50 mM | 0.0876 mL | 0.4379 mL | 0.8759 mL | 2.1897 mL | |
| 60 mM | 0.0730 mL | 0.3650 mL | 0.7299 mL | 1.8248 mL | |
| 80 mM | 0.0547 mL | 0.2737 mL | 0.5474 mL | 1.3686 mL | |
| 100 mM | 0.0438 mL | 0.2190 mL | 0.4379 mL | 1.0949 mL |
4-(2-Boc-aminoethyl)piperidine Related Classifications
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