4,4-Difluoropiperidine hydrochloride
Based on 1 Customer Validation
4,4-Difluoropiperidine hydrochloride is an intermediate. 4,4-Difluoropiperidine hydrochloride derivatives have anticancer activity against leukemia and pancreatic cancer.
For research use only. We do not sell to patients.
- Purity: 99.84%
- CAS No.: 144230-52-4
- Formula: C5H10ClF2N
- Molecular Weight:157.59
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 144230-52-4
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Appearance Solid
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Molecular Weight 157.59
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Formula C5H10ClF2N
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Color White to light yellow
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SMILES
FC1(F)CCNCC1.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (634.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Woods JR, et al. Fluorinated amino-derivatives of the sesquiterpene lactone, parthenolide, as (19)f NMR probes in deuterium-free environments. J Med Chem. 2011 Nov 24;54(22):7934-41. [Content Brief]
[2]. Xue D, et al. Multiparameter Optimization of Oxidative Phosphorylation Inhibitors for the Treatment of Pancreatic Cancer. J Med Chem. 2022 Feb 24;65(4):3404-3419. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.3456 mL | 31.7279 mL | 63.4558 mL | 158.6395 mL |
| 5 mM | 1.2691 mL | 6.3456 mL | 12.6912 mL | 31.7279 mL | |
| 10 mM | 0.6346 mL | 3.1728 mL | 6.3456 mL | 15.8640 mL | |
| 15 mM | 0.4230 mL | 2.1152 mL | 4.2304 mL | 10.5760 mL | |
| 20 mM | 0.3173 mL | 1.5864 mL | 3.1728 mL | 7.9320 mL | |
| 25 mM | 0.2538 mL | 1.2691 mL | 2.5382 mL | 6.3456 mL | |
| 30 mM | 0.2115 mL | 1.0576 mL | 2.1152 mL | 5.2880 mL | |
| 40 mM | 0.1586 mL | 0.7932 mL | 1.5864 mL | 3.9660 mL | |
| 50 mM | 0.1269 mL | 0.6346 mL | 1.2691 mL | 3.1728 mL | |
| 60 mM | 0.1058 mL | 0.5288 mL | 1.0576 mL | 2.6440 mL | |
| 80 mM | 0.0793 mL | 0.3966 mL | 0.7932 mL | 1.9830 mL | |
| 100 mM | 0.0635 mL | 0.3173 mL | 0.6346 mL | 1.5864 mL |
4,4-Difluoropiperidine hydrochloride Related Classifications
HY-W001440 Related Classifications
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