4',6,7-Trimethoxyisoflavone

Cat. No.: HY-133951 Purity: 97.04%: Data Sheet
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4',6,7-Trimethoxyisoflavone is an isoflavone with antimicrobial activities against a wide range of bacteria and fungi. 4',6,7-Trimethoxyisoflavone also has antioxidant effects.

For research use only. We do not sell to patients.

4',6,7-Trimethoxyisoflavone Chemical Structure

CAS No. : 798-61-8

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

4',6,7-Trimethoxyisoflavone is an isoflavone with antimicrobial activities against a wide range of bacteria and fungi. 4',6,7-Trimethoxyisoflavone also has antioxidant effects^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A-375	IC₅₀	> 10 μM Compound: 9ca	Growth inhibition of human A375 cells measured after 48 hrs by MTS assay Growth inhibition of human A375 cells measured after 48 hrs by MTS assay	[PMID: 27100701]
A549	IC₅₀	> 10 μM Compound: 9ca	Growth inhibition of human A549 cells by MTS assay Growth inhibition of human A549 cells by MTS assay	[PMID: 27100701]
DU-145	IC₅₀	> 10 μM Compound: 9ca	Growth inhibition of human DU145 cells measured after 48 hrs by MTS assay Growth inhibition of human DU145 cells measured after 48 hrs by MTS assay	[PMID: 27100701]
HCT-116	IC₅₀	> 10 μM Compound: 9ca	Growth inhibition of human HCT116 cells measured after 48 hrs by MTS assay Growth inhibition of human HCT116 cells measured after 48 hrs by MTS assay	[PMID: 27100701]
MDA-MB-231	IC₅₀	> 10 μM Compound: 9ca	Growth inhibition of human MDA-MB-231 cells measured after 48 hrs by MTS assay Growth inhibition of human MDA-MB-231 cells measured after 48 hrs by MTS assay	[PMID: 27100701]
PBMC	IC₅₀	> 10 μM Compound: 9ca	Growth inhibition of human PBMC cells measured after 48 hrs by MTS assay Growth inhibition of human PBMC cells measured after 48 hrs by MTS assay	[PMID: 27100701]
PC-3	IC₅₀	> 10 μM Compound: 9ca	Growth inhibition of human PC3 cells measured after 48 hrs by MTS assay Growth inhibition of human PC3 cells measured after 48 hrs by MTS assay	[PMID: 27100701]
SK-OV-3	IC₅₀	> 10 μM Compound: 9ca	Growth inhibition of human SKOV3 cells measured after 48 hrs by MTS assay Growth inhibition of human SKOV3 cells measured after 48 hrs by MTS assay	[PMID: 27100701]

Molecular Weight

312.32

Formula

C₁₈H₁₆O₅

CAS No.

798-61-8

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1C(C2=CC=C(OC)C=C2)=COC3=CC(OC)=C(OC)C=C13

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (160.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.2018 mL	16.0092 mL	32.0184 mL
5 mM	0.6404 mL	3.2018 mL	6.4037 mL
10 mM	0.3202 mL	1.6009 mL	3.2018 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 97.04%

Select Batch:

Data Sheet (268 KB) SDS (393 KB)

COA (247 KB) HNMR (244 KB) RP-HPLC (248 KB) MS (228 KB)

Handling Instructions (2659 KB)

References

[1]. Edwige P. Fodja Saaha, et al. Antimicrobial and Antioxidant Isoflavonoid Derivatives from the Roots of Amphimas pterocarpoides. Z. Naturforsch. 2013, 68b, 931-938.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.2018 mL	16.0092 mL	32.0184 mL	80.0461 mL
	5 mM	0.6404 mL	3.2018 mL	6.4037 mL	16.0092 mL
	10 mM	0.3202 mL	1.6009 mL	3.2018 mL	8.0046 mL
	15 mM	0.2135 mL	1.0673 mL	2.1346 mL	5.3364 mL
	20 mM	0.1601 mL	0.8005 mL	1.6009 mL	4.0023 mL
	25 mM	0.1281 mL	0.6404 mL	1.2807 mL	3.2018 mL
	30 mM	0.1067 mL	0.5336 mL	1.0673 mL	2.6682 mL
	40 mM	0.0800 mL	0.4002 mL	0.8005 mL	2.0012 mL
	50 mM	0.0640 mL	0.3202 mL	0.6404 mL	1.6009 mL
	60 mM	0.0534 mL	0.2668 mL	0.5336 mL	1.3341 mL
	80 mM	0.0400 mL	0.2001 mL	0.4002 mL	1.0006 mL
	100 mM	0.0320 mL	0.1601 mL	0.3202 mL	0.8005 mL