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Cat. No.: HY-W614583

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4-Aminonaphthalen-1-yl acetate

4-Aminonaphthalen-1-yl acetate is a 4-amino-1-naphthol derivative and a negative control reagent for lysine (K) acetyltransferase KAT8. 4-Aminonaphthalen-1-yl acetate shows no activity against KAT8.

For research use only. We do not sell to patients.

CAS No.: 858186-27-3
Formula: C₁₂H₁₁NO₂
Molecular Weight:201.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

4-Aminonaphthalen-1-yl acetate Chemical Structure

CAS No.: 858186-27-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

All Histone Acetyltransferase Isoforms :

In Vitro

4-Aminonaphthalen-1-yl acetate (compound 23) (0-1 mM; 15 min) shows no significant inhibitory activity against recombinant human KAT8, with an IC₅₀ >500 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 858186-27-3
Molecular Weight 201.23
Formula C₁₂H₁₁NO₂
SMILES

O=C(OC1=CC=C(N)C=2C=CC=CC12)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wapenaar H, et al. The relevance of K_i calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor. Eur J Med Chem. 2017;136:480-486. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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4-Aminonaphthalen-1-yl acetate

All Histone Acetyltransferase Isoforms