4-Arm-PEG10000-Vinyl sulfone
Based on 1 Customer Validation
4-Arm-PEG10000-Vinyl sulfone (4-Arm-PEG10000-VS) is a four-armed PEG derivative. The core structure of 4-Arm-PEG10000-Vinyl sulfone consists of four PEG chains, each modified at the end with a vinyl sulfone (Vinyl sulfone) group. 4-Arm-PEG10000-Vinyl sulfone can be used for bioconjugation and drug delivery.
For research use only. We do not sell to patients.
- CAS No.: 860027-46-9
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
The structure of PEG-Vinyl sulfon comprises two key parts that work synergistically:
Vinyl sulfon group: This group can undergo a Michael addition reaction with free thiol groups on peptides and proteins to form a very stable thioether bond.
PEG chain: Acting as a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 860027-46-9
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Appearance Solid
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Color White to off-white
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SMILES
O=S(CCOCCOCC(COCCOCCS(C=C)(=O)=O)(COCCOCCS(C=C)(=O)=O)COCCOCCS(=O)(C=C)=O)(C=C)=O.[n].[n].[n].[n]
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Synonyms
4-Arm-PEG10000-VS
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Arm-PEG10000-Vinyl sulfone Related Classifications
HY-W1048867B Related Classifications
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