4-Cyanobutanoic acid
Based on 1 Customer Validation
4-Cyanobutanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.96%
- CAS No.: 39201-33-7
- Formula: C5H7NO2
- Molecular Weight:113.12
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E386 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 39201-33-7
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Appearance Solid
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Molecular Weight 113.12
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Formula C5H7NO2
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Color Off-white to light yellow
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SMILES
N#CCCCC(=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (884.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (641 KB)
- English - EN (641 KB)
- Français - FR (641 KB)
- Deutsch - DE (641 KB)
- Norwegian - NO (641 KB)
- Español - ES (641 KB)
- Swedish - SV (641 KB)
- Italian - IT (641 KB)
- Korean - KR (641 KB)
- Portuguese - PT (641 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.8402 mL | 44.2008 mL | 88.4017 mL | 221.0042 mL |
| 5 mM | 1.7680 mL | 8.8402 mL | 17.6803 mL | 44.2008 mL | |
| 10 mM | 0.8840 mL | 4.4201 mL | 8.8402 mL | 22.1004 mL | |
| 15 mM | 0.5893 mL | 2.9467 mL | 5.8934 mL | 14.7336 mL | |
| 20 mM | 0.4420 mL | 2.2100 mL | 4.4201 mL | 11.0502 mL | |
| 25 mM | 0.3536 mL | 1.7680 mL | 3.5361 mL | 8.8402 mL | |
| 30 mM | 0.2947 mL | 1.4734 mL | 2.9467 mL | 7.3668 mL | |
| 40 mM | 0.2210 mL | 1.1050 mL | 2.2100 mL | 5.5251 mL | |
| 50 mM | 0.1768 mL | 0.8840 mL | 1.7680 mL | 4.4201 mL | |
| 60 mM | 0.1473 mL | 0.7367 mL | 1.4734 mL | 3.6834 mL | |
| 80 mM | 0.1105 mL | 0.5525 mL | 1.1050 mL | 2.7626 mL | |
| 100 mM | 0.0884 mL | 0.4420 mL | 0.8840 mL | 2.2100 mL |
4-Cyanobutanoic acid Related Classifications
HY-W018031 Related Classifications
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