4-Hydroxy-3,3',5-trimethoxybibenzyl
4-Hydroxy-3,3',5-trimethoxybibenzyl is a synthetic bibenzyl analog with spasmolytic activity. It inhibits spontaneous contractions of isolated guinea pig ileum. In the presence of Ca2+, 4-Hydroxy-3,3',5-trimethoxybibenzyl also alters the electrophoretic mobility of bovine brain calmodulin (calmodulin), supporting its interaction with CaM. It can be used in studies of smooth muscle contraction and calmodulin-related processes.
For research use only. We do not sell to patients.
- CAS No.: 213842-42-3
- Formula: C17H20O4
- Molecular Weight:288.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
4-Hydroxy-3,3',5-trimethoxybibenzyl (compound 23) (10 min) inhibits the spontaneous contraction of isolated guinea pig ileum, with an IC50 of 1.39 µM and a maximum inhibition rate of 76.40%[1].
4-Hydroxy-3,3',5-trimethoxybibenzyl binds to bovine brain CaM in the presence of Ca2+, as confirmed by the retardation of electrophoretic mobility in SDS-PAGE[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 213842-42-3
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Molecular Weight 288.34
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Formula C17H20O4
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SMILES
OC1=CC=C(C=C1OC)CCC=2C=C(OC)C=C(OC)C2
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Hydroxy-3,3',5-trimethoxybibenzyl Related Classifications
HY-N21792 Related Classifications
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