4-(Prop-2-yn-1-yloxy)piperidine hydrochloride
Based on 1 Customer Validation
4-(Prop-2-yn-1-yloxy)piperidine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 1185100-09-7
- Formula: C8H14ClNO
- Molecular Weight:175.66
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E357 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1185100-09-7
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Appearance Solid
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Molecular Weight 175.66
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Formula C8H14ClNO
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Color White to light yellow
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SMILES
Cl.C#CCOC1CCNCC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (569.28 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (241 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.6928 mL | 28.4641 mL | 56.9282 mL | 142.3204 mL |
| 5 mM | 1.1386 mL | 5.6928 mL | 11.3856 mL | 28.4641 mL | |
| 10 mM | 0.5693 mL | 2.8464 mL | 5.6928 mL | 14.2320 mL | |
| 15 mM | 0.3795 mL | 1.8976 mL | 3.7952 mL | 9.4880 mL | |
| 20 mM | 0.2846 mL | 1.4232 mL | 2.8464 mL | 7.1160 mL | |
| 25 mM | 0.2277 mL | 1.1386 mL | 2.2771 mL | 5.6928 mL | |
| 30 mM | 0.1898 mL | 0.9488 mL | 1.8976 mL | 4.7440 mL | |
| 40 mM | 0.1423 mL | 0.7116 mL | 1.4232 mL | 3.5580 mL | |
| 50 mM | 0.1139 mL | 0.5693 mL | 1.1386 mL | 2.8464 mL | |
| 60 mM | 0.0949 mL | 0.4744 mL | 0.9488 mL | 2.3720 mL | |
| 80 mM | 0.0712 mL | 0.3558 mL | 0.7116 mL | 1.7790 mL | |
| 100 mM | 0.0569 mL | 0.2846 mL | 0.5693 mL | 1.4232 mL |