5-Aminopentane-1-thiol hydrochloride
5-Aminopentane-1-thiol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.95%
- CAS No.: 31110-78-8
- Formula: C5H14ClNS
- Molecular Weight:155.69
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E404 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 31110-78-8
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Appearance Solid
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Molecular Weight 155.69
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Formula C5H14ClNS
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Color White to off-white
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SMILES
SCCCCCN.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (321.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (239 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.4230 mL | 32.1151 mL | 64.2302 mL | 160.5755 mL |
| 5 mM | 1.2846 mL | 6.4230 mL | 12.8460 mL | 32.1151 mL | |
| 10 mM | 0.6423 mL | 3.2115 mL | 6.4230 mL | 16.0576 mL | |
| 15 mM | 0.4282 mL | 2.1410 mL | 4.2820 mL | 10.7050 mL | |
| 20 mM | 0.3212 mL | 1.6058 mL | 3.2115 mL | 8.0288 mL | |
| 25 mM | 0.2569 mL | 1.2846 mL | 2.5692 mL | 6.4230 mL | |
| 30 mM | 0.2141 mL | 1.0705 mL | 2.1410 mL | 5.3525 mL | |
| 40 mM | 0.1606 mL | 0.8029 mL | 1.6058 mL | 4.0144 mL | |
| 50 mM | 0.1285 mL | 0.6423 mL | 1.2846 mL | 3.2115 mL | |
| 60 mM | 0.1071 mL | 0.5353 mL | 1.0705 mL | 2.6763 mL | |
| 80 mM | 0.0803 mL | 0.4014 mL | 0.8029 mL | 2.0072 mL | |
| 100 mM | 0.0642 mL | 0.3212 mL | 0.6423 mL | 1.6058 mL |
5-Aminopentane-1-thiol hydrochloride Related Classifications
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