5-Bromopentan-1-amine hydrobromide
Based on 1 Customer Validation
5-Bromopentan-1-amine hydrobromide is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥96.0%
- CAS No.: 51874-27-2
- Formula: C5H13Br2N
- Molecular Weight:246.97
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E406 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 51874-27-2
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Appearance Solid
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Molecular Weight 246.97
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Formula C5H13Br2N
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Color White to off-white
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SMILES
BrCCCCCN.Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (404.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (238 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0491 mL | 20.2454 mL | 40.4907 mL | 101.2269 mL |
| 5 mM | 0.8098 mL | 4.0491 mL | 8.0981 mL | 20.2454 mL | |
| 10 mM | 0.4049 mL | 2.0245 mL | 4.0491 mL | 10.1227 mL | |
| 15 mM | 0.2699 mL | 1.3497 mL | 2.6994 mL | 6.7485 mL | |
| 20 mM | 0.2025 mL | 1.0123 mL | 2.0245 mL | 5.0613 mL | |
| 25 mM | 0.1620 mL | 0.8098 mL | 1.6196 mL | 4.0491 mL | |
| 30 mM | 0.1350 mL | 0.6748 mL | 1.3497 mL | 3.3742 mL | |
| 40 mM | 0.1012 mL | 0.5061 mL | 1.0123 mL | 2.5307 mL | |
| 50 mM | 0.0810 mL | 0.4049 mL | 0.8098 mL | 2.0245 mL | |
| 60 mM | 0.0675 mL | 0.3374 mL | 0.6748 mL | 1.6871 mL | |
| 80 mM | 0.0506 mL | 0.2531 mL | 0.5061 mL | 1.2653 mL | |
| 100 mM | 0.0405 mL | 0.2025 mL | 0.4049 mL | 1.0123 mL |