6-Chloro-7-hydroxy-4-methylcoumarin
Based on 1 Customer Validation
6-Chloro-7-hydroxy-4-methylcoumarin (compound 3) an intermediate of pharmaceutical synthesis.
For research use only. We do not sell to patients.
- Purity: 99.56%
- CAS No.: 19492-02-5
- Formula: C10H7ClO3
- Molecular Weight:210.61
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U-937 | CC50 |
734.3 μM
Compound: 9
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Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay
Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay
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[PMID: 22925447] |
| U-937 | IC50 |
771.3 μM
Compound: 9
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Antiproliferative activity against human U937 cells assessed as incorporation of [3H]-methyl-thymidine after 12 hrs by scintillation counting
Antiproliferative activity against human U937 cells assessed as incorporation of [3H]-methyl-thymidine after 12 hrs by scintillation counting
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[PMID: 22925447] |
Chemical Information
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CAS No. 19492-02-5
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Appearance Solid
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Molecular Weight 210.61
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Formula C10H7ClO3
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Color Off-white to gray
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SMILES
O=C1C=C(C)C2=CC(Cl)=C(O)C=C2O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (237.41 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7481 mL | 23.7406 mL | 47.4811 mL | 118.7028 mL |
| 5 mM | 0.9496 mL | 4.7481 mL | 9.4962 mL | 23.7406 mL | |
| 10 mM | 0.4748 mL | 2.3741 mL | 4.7481 mL | 11.8703 mL | |
| 15 mM | 0.3165 mL | 1.5827 mL | 3.1654 mL | 7.9135 mL | |
| 20 mM | 0.2374 mL | 1.1870 mL | 2.3741 mL | 5.9351 mL | |
| 25 mM | 0.1899 mL | 0.9496 mL | 1.8992 mL | 4.7481 mL | |
| 30 mM | 0.1583 mL | 0.7914 mL | 1.5827 mL | 3.9568 mL | |
| 40 mM | 0.1187 mL | 0.5935 mL | 1.1870 mL | 2.9676 mL | |
| 50 mM | 0.0950 mL | 0.4748 mL | 0.9496 mL | 2.3741 mL | |
| 60 mM | 0.0791 mL | 0.3957 mL | 0.7914 mL | 1.9784 mL | |
| 80 mM | 0.0594 mL | 0.2968 mL | 0.5935 mL | 1.4838 mL | |
| 100 mM | 0.0475 mL | 0.2374 mL | 0.4748 mL | 1.1870 mL |
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