6-Chloropurine-2'-deoxyriboside
Based on 1 Customer Validation
6-Chloropurine-2'-deoxyriboside is a monomeric raw material that can be used for nucleic acid synthesis.
For research use only. We do not sell to patients.
- Purity : 99.53%
- CAS No.: 4594-45-0
- Formula: C10H11ClN4O3
- Molecular Weight:270.68
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
173 μM
Compound: 9
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Cytotoxicity against Huh7 cells by XTT assay
Cytotoxicity against Huh7 cells by XTT assay
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[PMID: 17766124] |
| Huh-7 | EC50 |
47.2 μM
Compound: 3
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Antiviral activity against HCV assessed as inhibition of viral RNA replication in Huh7 cells
Antiviral activity against HCV assessed as inhibition of viral RNA replication in Huh7 cells
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[PMID: 18644724] |
| Huh-7 | EC50 |
47.2 μM
Compound: 9
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Inhibition of HCV replication in Huh7 cells after 48 hrs by luciferase assay
Inhibition of HCV replication in Huh7 cells after 48 hrs by luciferase assay
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[PMID: 17766124] |
| Vero | IC50 |
>300 μM
Compound: 6
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Antiviral activity against SARS-CoV Frankfurt1 in Vero E6 cells by plaque reduction assay
Antiviral activity against SARS-CoV Frankfurt1 in Vero E6 cells by plaque reduction assay
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[PMID: 17336519] |
Chemical Information
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CAS No. 4594-45-0
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Appearance Solid
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Molecular Weight 270.68
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Formula C10H11ClN4O3
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Color White to off-white
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SMILES
OC[C@@H]1[C@@H](O)C[C@H](N2C(N=CN=C3Cl)=C3N=C2)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 25 mg/mL (92.36 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (247 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.6944 mL | 18.4720 mL | 36.9440 mL | 92.3600 mL |
| 5 mM | 0.7389 mL | 3.6944 mL | 7.3888 mL | 18.4720 mL | |
| 10 mM | 0.3694 mL | 1.8472 mL | 3.6944 mL | 9.2360 mL | |
| 15 mM | 0.2463 mL | 1.2315 mL | 2.4629 mL | 6.1573 mL | |
| 20 mM | 0.1847 mL | 0.9236 mL | 1.8472 mL | 4.6180 mL | |
| 25 mM | 0.1478 mL | 0.7389 mL | 1.4778 mL | 3.6944 mL | |
| 30 mM | 0.1231 mL | 0.6157 mL | 1.2315 mL | 3.0787 mL | |
| 40 mM | 0.0924 mL | 0.4618 mL | 0.9236 mL | 2.3090 mL | |
| 50 mM | 0.0739 mL | 0.3694 mL | 0.7389 mL | 1.8472 mL | |
| 60 mM | 0.0616 mL | 0.3079 mL | 0.6157 mL | 1.5393 mL | |
| 80 mM | 0.0462 mL | 0.2309 mL | 0.4618 mL | 1.1545 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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