1. Membrane Transporter/Ion Channel
  2. P2X Receptor
  3. 8-Bromo-ATP

8-Bromo-ATP (Synonyms: 8-Bromoadenosine 5'-triphosphate; 8-Br-ATP)

Cat. No.: HY-134262
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8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate), an ATP analogue, is a purinergic P2X receptor agonist. 8-Bromo-ATP shows cytotoxic to multiple myeloma cells with an IC50 of 23.1 μM.

For research use only. We do not sell to patients.

8-Bromo-ATP Chemical Structure

8-Bromo-ATP Chemical Structure

CAS No. : 23567-97-7

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Description

8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate), an ATP analogue, is a purinergic P2X receptor agonist. 8-Bromo-ATP shows cytotoxic to multiple myeloma cells with an IC50 of 23.1 μM[1][2][3].

In Vitro

8-Bromo-ATP (10-50 μM; 5 days) treatment shows cytotoxic to multiple myeloma[3].
Fluorescence measurements are made possible through the use of 8-Bromo-ATP, which selectively quenched certain tryptophan residues of the ATPase. 8-Bromo-ATP enhances the rate of dephosphorylation of native ATPase 2-3-fold when added in the absence of divalent cations[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[3]

Cell Line: MM 1.s cells
Concentration: 10 μM, 20 μM, 30 μM, 40 μM, 50 μM
Incubation Time: 5 days
Result: Showed cytotoxic to multiple myeloma.
Molecular Weight

586.08

Formula

C₁₀H₁₅BrN₅O₁₃P₃

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8-Bromo-ATP
Cat. No.:
HY-134262
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