(9H-Fluoren-9-yl)methyl (2-hydroxyethyl)carbamate
Based on 1 Customer Validation
(9H-Fluoren-9-yl)methyl (2-hydroxyethyl)carbamate (N-Fmoc-ethanolamine) is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.93%
- CAS No.: 105496-31-9
- Formula: C17H17NO3
- Molecular Weight:283.33
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E25 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 105496-31-9
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Appearance Solid
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Molecular Weight 283.33
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Formula C17H17NO3
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Color White to off-white
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SMILES
O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NCCO
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Synonyms
N-Fmoc-ethanolamine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (176.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (244 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5295 mL | 17.6473 mL | 35.2945 mL | 88.2363 mL |
| 5 mM | 0.7059 mL | 3.5295 mL | 7.0589 mL | 17.6473 mL | |
| 10 mM | 0.3529 mL | 1.7647 mL | 3.5295 mL | 8.8236 mL | |
| 15 mM | 0.2353 mL | 1.1765 mL | 2.3530 mL | 5.8824 mL | |
| 20 mM | 0.1765 mL | 0.8824 mL | 1.7647 mL | 4.4118 mL | |
| 25 mM | 0.1412 mL | 0.7059 mL | 1.4118 mL | 3.5295 mL | |
| 30 mM | 0.1176 mL | 0.5882 mL | 1.1765 mL | 2.9412 mL | |
| 40 mM | 0.0882 mL | 0.4412 mL | 0.8824 mL | 2.2059 mL | |
| 50 mM | 0.0706 mL | 0.3529 mL | 0.7059 mL | 1.7647 mL | |
| 60 mM | 0.0588 mL | 0.2941 mL | 0.5882 mL | 1.4706 mL | |
| 80 mM | 0.0441 mL | 0.2206 mL | 0.4412 mL | 1.1030 mL | |
| 100 mM | 0.0353 mL | 0.1765 mL | 0.3529 mL | 0.8824 mL |
(9H-Fluoren-9-yl)methyl (2-hydroxyethyl)carbamate Related Classifications
HY-W011533 Related Classifications
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