1. Cell Cycle/DNA Damage
    Epigenetics
  2. HDAC
  3. AES-135

AES-135 

Cat. No.: HY-114483
Handling Instructions

AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 with IC50s of 654, 190, and 636 nM, respectively. Anti-tumor activity.

For research use only. We do not sell to patients.

AES-135 Chemical Structure

AES-135 Chemical Structure

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Description

AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 with IC50s of 654, 190, and 636 nM, respectively. Anti-tumor activity[1].

IC50 & Target[1]

HDAC6

190 nM (IC50)

HDAC11

636 nM (IC50)

HDAC3

654 nM (IC50)

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

693.66

Formula

C₃₃H₂₉F₆N₃O₅S

SMILES

CC(C)(C)C1=CC=C(CN(C(CN(CC2=C(F)C(F)=C(F)C(F)=C2F)S(=O)(C3=CC=C(F)C=C3)=O)=O)C4=CC=C(C(NO)=O)C=C4)C=C1

Shipping

Room temperature in continental US; may vary elsewhere

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
AES-135
Cat. No.:
HY-114483
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AES-135

Cat. No.: HY-114483