1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor

Cyproheptadine hydrochloride 

Cat. No.: HY-B0366A Purity: 98.96%
Handling Instructions

Cyproheptadine is a histamine receptor antagonist for 5-HT2 receptor with IC50 of 0.6 nM.

For research use only. We do not sell to patients.

Cyproheptadine hydrochloride Chemical Structure

Cyproheptadine hydrochloride Chemical Structure

CAS No. : 969-33-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
50 mg USD 60 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
100 mg USD 72 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
500 mg USD 84 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
1 g USD 108 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
5 g   Get quote  
10 g   Get quote  

* Please select Quantity before adding items.

Other Forms of Cyproheptadine hydrochloride:

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Cyproheptadine is a histamine receptor antagonist for 5-HT2 receptor with IC50 of 0.6 nM. Target: 5-HT2 Receptor Cyproheptadine is a serotonin antagonist and a histamine H2 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc. Inhibitory effects of cyclobenzaprine, amitriptyline, and cyproheptadine on mono- and polysynaptic reflex potentials are due to the inhibition of descending serotonergic systems through 5-HT(2) receptors in the spinal cord [1, 2].

Clinical Trial
References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 3.0878 mL 15.4388 mL 30.8775 mL
5 mM 0.6176 mL 3.0878 mL 6.1755 mL
10 mM 0.3088 mL 1.5439 mL 3.0878 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

323.86

Formula

C₂₁H₂₂ClN

CAS No.

969-33-5

SMILES

CN1CC/C(CC1)=C2C3=CC=CC=C3C=CC4=CC=CC=C/24.Cl

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Cyproheptadine hydrochloride
Cat. No.:
HY-B0366A
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