1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor

Cyproheptadine hydrochloride 

Cat. No.: HY-B0366A Purity: 99.87%
Data Sheet SDS Handling Instructions

Cyproheptadine is a histamine receptor antagonist for 5-HT2 receptor with IC50 of 0.6 nM.

For research use only. We do not sell to patients.
Cyproheptadine hydrochloride Chemical Structure

Cyproheptadine hydrochloride Chemical Structure

CAS No. : 969-33-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
50 mg USD 60 In-stock
100 mg USD 72 In-stock
500 mg USD 84 In-stock
1 g USD 108 In-stock
5 g   Get quote  
10 g   Get quote  

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Other Forms of Cyproheptadine hydrochloride:

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  • Protocol

  • Technical Information

  • Purity & Documentation

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Cyproheptadine is a histamine receptor antagonist for 5-HT2 receptor with IC50 of 0.6 nM. Target: 5-HT2 Receptor Cyproheptadine is a serotonin antagonist and a histamine H2 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc. Inhibitory effects of cyclobenzaprine, amitriptyline, and cyproheptadine on mono- and polysynaptic reflex potentials are due to the inhibition of descending serotonergic systems through 5-HT(2) receptors in the spinal cord [1, 2].

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Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 3.0878 mL 15.4388 mL 30.8775 mL
5 mM 0.6176 mL 3.0878 mL 6.1755 mL
10 mM 0.3088 mL 1.5439 mL 3.0878 mL
Please refer to the solubility information to select the appropriate solvent.
Molecular Weight






Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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