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DL-threo-2-methylisocitrate 

Cat. No.: HY-16581
Handling Instructions

DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1(ICL1).

For research use only. We do not sell to patients.

DL-threo-2-methylisocitrate Chemical Structure

DL-threo-2-methylisocitrate Chemical Structure

CAS No. : 71183-66-9

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Description

DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1(ICL1). IC50 value: Target: The Km of purified recombinant ICL1 for threo-D(s)L(s)-isocitrate (ICA) was determined to be 188 μM using Michaelis-Menten non-linear least squares fit, with a kcat of 5.24 s-1. The Km for DL-threo-2-methylisocitrate (MICA) was approximately fourfold higher at 718 μM with a kcat of 1.25 s-1.

Molecular Weight

412.30

Formula

C₁₄H₂₀O₁₄

CAS No.

71183-66-9

SMILES

O[[email protected]@](C)(C(O)=O)[[email protected]@]([H])(C(O)=O)CC(O)=O.O[[email protected]](C)(C(O)=O)[[email protected]]([H])(C(O)=O)CC(O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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DL-threo-2-methylisocitrate
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HY-16581
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