1. Metabolic Enzyme/Protease
  2. Acetyl-CoA Carboxylase
  3. Firsocostat (S enantiomer)

Firsocostat (S enantiomer)  (Synonyms: ND-630 (S enantiomer); GS-0976 (S enantiomer); NDI-010976 (S enantiomer))

Cat. No.: HY-16901A Purity: 98.14%
COA Handling Instructions

Firsocostat S enantiomer (ND-630 S enantiomer) is the less active S enantiomer of Firsocostat. Firsocostat is an acetyl-CoA carboxylase (ACC) inhibitor.

For research use only. We do not sell to patients.

Firsocostat (S enantiomer) Chemical Structure

Firsocostat (S enantiomer) Chemical Structure

CAS No. : 2128714-16-7

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5 mg USD 900 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Firsocostat (S enantiomer):

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Description

Firsocostat S enantiomer (ND-630 S enantiomer) is the less active S enantiomer of Firsocostat. Firsocostat is an acetyl-CoA carboxylase (ACC) inhibitor.

Molecular Weight

569.63

Formula

C28H31N3O8S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C(C(C)=C(C1=NC=CO1)S2)=C2N3C[C@@H](OC4CCOCC4)C5=C(OC)C=CC=C5)N(C(C)(C)C(O)=O)C3=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (87.78 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7555 mL 8.7776 mL 17.5553 mL
5 mM 0.3511 mL 1.7555 mL 3.5111 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7555 mL 8.7776 mL 17.5553 mL 43.8881 mL
5 mM 0.3511 mL 1.7555 mL 3.5111 mL 8.7776 mL
10 mM 0.1756 mL 0.8778 mL 1.7555 mL 4.3888 mL
15 mM 0.1170 mL 0.5852 mL 1.1704 mL 2.9259 mL
20 mM 0.0878 mL 0.4389 mL 0.8778 mL 2.1944 mL
25 mM 0.0702 mL 0.3511 mL 0.7022 mL 1.7555 mL
30 mM 0.0585 mL 0.2926 mL 0.5852 mL 1.4629 mL
40 mM 0.0439 mL 0.2194 mL 0.4389 mL 1.0972 mL
50 mM 0.0351 mL 0.1756 mL 0.3511 mL 0.8778 mL
60 mM 0.0293 mL 0.1463 mL 0.2926 mL 0.7315 mL
80 mM 0.0219 mL 0.1097 mL 0.2194 mL 0.5486 mL
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Firsocostat (S enantiomer) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Firsocostat (S enantiomer)
Cat. No.:
HY-16901A
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