Others

Domusiran (ALY-101) is a Jak-1 inhibitor.

Pinzodirsen delvopertide is a fully P-chiral isomer-modified peptide-oligonucleotide conjugate (POC) and a steric blocker targeting myotonic dystrophy protein kinase (DMPK). Pinzodirsen delvopertide is applicable to mechanism research on myotonic dystrophy-related targets.

Zulaporsen rocopertide can promote the synthesis of optic atrophy 1 (OPA1) protein.

DMT-dC(NMe)-CE Phosphoramidite is a modified phosphoramidite monomer that can be used for the synthesis of oligonucleotides.

NSC-41589 is N-[2-(methylsulfanyl) phenyl]acetamide.

5'-Amino-modifier spacer 18 Phosphoramidite is a modified phosphoramidite monomer that can be used for the synthesis of oligonucleotides.

5'-Amino-modifier spacer 9 Phosphoramidite is a modified phosphoramidite monomer that can be used for the synthesis of oligonucleotides.

5'-Di-Fmoc-amino-modifier 11 Phosphoramidite is a modified phosphoramidite monomer that can be used for the synthesis of oligonucleotides.

5'-Di-TFA-amino-modifier Phosphoramidite is a modified phosphoramidite monomer that can be used in the synthesis of oligonucleotides.

Amino-modifier C3 Phosphoramidite is a modified phosphoramidite monomer that can be used in oligonucleotide synthesis.

Alkyne-modifier dT Phosphoramidite is a functionalized phosphoramidite monomer that can be used in DNA solid-phase synthesis to attach a terminal alkynyl (-C≡CH) handle at a specific position on the oligonucleotide chain.

5'-Aqp 639 Phosphoramidite is a far-red fluorescent azaphosphoramide monomer of the rhodamine type, which is used for directly introducing the AP639 fluorophore at the 5' end during DNA/RNA solid-phase synthesis.

CBEmax mRNA (N1-methyl-pseudouridine) is an optimized cytosine base editor, CBEmax, that converts C·G to T·A for precise base editing and disease model research.

eSpCas9 mRNA (N1-methyl-pseudouridine) is a high-fidelity version of SpCas9 with lower off-target rates while maintaining high targeted genome editing efficiency.

eGFP Self-Amplifying RNA (5-methylcytidine) is a self-amplifying RNA encoding enhanced green fluorescent protein eGFP, which can be expressed for extended periods at low doses and is used as a reporter gene and transfection tracing gene. The expressed protein is excited at 488 nm and emitted at 507 nm.

F-Luc Self-Amplifying RNA (5-methylcytidine) is a self-amplifying RNA encoding the firefly luciferase F-Luc, used for in vivo bioluminescence imaging and quantitative gene expression detection. After efficiently entering cells or animals, F-Luc mRNA can be translated into F-Luc and emit bioluminescence in the presence of its substrate, luciferin.

hEPO mRNA (N1-methyl-pseudouridine) is an enzyme encoding human erythropoietin (hEPO) used for protein expression, functional studies, and the exploration of erythropoiesis-related diseases.

mNeptune2.5 mRNA (N1-methyl-pseudouridine) is a far-red fluorescent protein, mNeptune2.5, with strong tissue penetration, used for deep in vivo fluorescence imaging and tracing. mNeptune2.5 protein can be excited in the visible light range at wavelengths greater than 600 nm.

saCas9 mRNA (N1-methyl-pseudouridine) is an enzyme encoding Staphylococcus aureus Cas9 (saCas9), small in size and well-suited for AAV delivery. After efficiently entering cells or animals, saCas9 mRNA (N1-methyl-pseudouridine) can be translated into protein, thereby enabling gene editing functions within the cell.

SB100 mRNA (N1-methyl-pseudouridine) is an enzyme encoding Sleeping Beauty transposase SB100, which catalyzes transposon integration for stabilizing transgenes and gene delivery.