Others

NE58018 is a compound with bone resorption inhibitory activity. NE58018 exerts its effect by affecting the action of Farnesyl pyrophosphate synthase (FPPS). The structural features of NE58018 combined with aminophosphonates significantly enhance its inhibitory activity. NE58018 affects the roles of Thr201 and Tyr204 residues in substrate binding and catalysis. The interaction of NE58018 enhances the inhibitory effect on the target enzyme.

Nonacosadiene is the pheromone of Drosophila melanogaster from a tetrahydrophyridine derivative.

NY-0173 is an antagonist of Exchange proteins directly activated by cAMP (EPAC), with IC₅₀s of 3.5 μM (EPAC2)and 4.0 μM (EPAC1) respectively. NY-0173 can be used to elucidate the biological functions of EPAC.

Piperophos (Standard) is the analytical standard of Piperophos. This product is intended for research and analytical applications. Piperophos (C-19490) is an herbicide.

PNU-107484A is a GABA_A receptor ligand that exhibits target activity mechanisms dependent on α isoforms. In the α1β2γ2 subtype, PNU-107484A acts as a positive allosteric modulator, enhancing GABA-induced Cl^- currents, while it inhibits the currents in the α3β2γ2 and α6β2γ2 subtypes. The half-maximal concentrations for the α1β2γ2, α3β2γ2, and α6β2γ2 subtypes are 3.1, 4.2, and 3.5 μM, respectively. PNU-107484A can be used as a probe to investigate the physiological roles of different α isoform subtypes.

Amino Tadalafil (Standard) is the analytical standard of Amino Tadalafil. This product is intended for research and analytical applications. Amino Tadalafil is a structural analogue of Tadalafil (HY-90009A). Tadalafil is a potent inhibitor of PDE5 with applications in several conditions, including erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.

Hexamethoxymethylmelamine (Hexakis(methoxymethyl)melamine; HMMM) is a type of multifunctional melamine-formaldehyde crosslinker. Under acid-catalyzed conditions, Hexamethoxymethylmelamine enables chemical crosslinking between hydroxyl-functionalized polymers and hydroxyl groups in coating systems via methoxy-hydroxyl reactions, forming an interconnected network structure. Hexamethoxymethylmelamine can be used in organic synthesis-related research, such as thermosetting coatings.

BMS-337197 is an inosine monophosphate dehydrogenase (IMPDH) inhibitor.

Quizalofop-P (Standard) is the analytical standard of Quizalofop-P. This product is intended for research and analytical applications. Quizalofop-P is absorbed through weed stems and leaves, conducts upward and downward in plants, accumulates at the top and intermediate meristems, inhibits cellular fatty acid synthesis, and makes weeds necrotic. Quizalofop-P is highly selective between grass weeds and dicotyledonous crops.

4-trans-Hydroxy glibenclamide-d₅ is deuterated labeled 4-trans-Hydroxy glibenclamide.

4-trans-Hydroxy glibenclamide-¹³C,d₄ is ¹³C and deuterated labeled 4-trans-Hydroxy glibenclamide.

Proquinazid-(propoxy-d₇) (6-Iodo-2-propoxy-d₇-3-propyl-4(3H)-quinazolinone) is deuterium labeled Proquinazid.

Pantoprazole sulfone is the major metabolite of Pantoprazole (HY-17507), which is a potent H⁺/K⁺-ATPase inhibitor.

Triflusulfuron-methyl (DPX 66037) is an active compound.

Ketomethylenebestatin is an aminopeptidase (AP) inhibitor and an analog of the natural aminopeptidase inhibitor Bestatin (HY-B0134) with IC₅₀ of 56 μM, 752 μM and 0.39 μM for AP-B, AP-M and Leu-AP, respectively.

ZM260384 is a K_ATP channel opener that accelerates metabolism and inhibits the decline of guinea pig isolated diaphragm function, thereby affecting muscle contraction. ZM260384 can be used to study muscle function under hypoxic conditions.

Propaquizafop (Standard) is the analytical standard of Propaquizafop. This product is intended for research and analytical applications. Propaquizafop is a phenoxyisopropionic acid herbicide and an acetyl-coA carboxylase inhibitor.

(2R,3R)-2,3,4-Trihydroxybutanoic acid, also known as erythronic acid, is a naturally occurring organic acid found in the aqueous humor of the eye, as well as in urine, plasma, cerebrospinal fluid, and synovial fluid, prevalent in both healthy adults and children; it is produced through the oxidation of GlcNAc.

(S)-Metolachor (Standard) is the analytical standard of (S)-Metolachor. This product is intended for research and analytical applications. (S)-Metolachor, a derivative of aniline, is a major pesticide in use.

Spirotryprostatin A is a natural product.