2. Apoptosis
  3. Ferroptosis
  4. Petadeferitrin

Petadeferitrin (SP-420) is a tridentate iron chelator belonging to the class of iron chelators, with orally activity. Petadeferitrin can be used in research related to β-thalassemia.

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Petadeferitrin

Petadeferitrin 화학구조

CAS No. : 911714-45-9

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Petadeferitrin Related Antibodies

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제품 설명

Petadeferitrin (SP-420) is a tridentate iron chelator belonging to the class of iron chelators, with orally activity. Petadeferitrin can be used in research related to β-thalassemia[1][2][3].

In Vitro

Petadeferitrin is a derivative of Desferrithiocin but has higher iron clearance efficiency compared to Desferrithiocin with an ICE (Iron Clearance Efficiency) value of 26.7[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Petadeferitrin Related Antibodies
In Vivo

Petadeferitrin causes renal function abnormalities, including increased serum creatinine, proteinuria, increased urine protein/creatinine ratio, and glycosuria[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
분자량

355.41

화학식

C16H21NO6S
CAS No.
Appearance

Solid

Color

Light yellow to khaki

SMILES

O=C([C@]1(C)N=C(C2=CC=C(OCCOCCOC)C=C2O)SC1)O
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
용액&용해도
In Vitro: 

DMSO : ≥ 38 mg/mL (106.92 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8137 mL 14.0683 mL 28.1365 mL
5 mM 0.5627 mL 2.8137 mL 5.6273 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8137 mL 14.0683 mL 28.1365 mL 70.3413 mL
5 mM 0.5627 mL 2.8137 mL 5.6273 mL 14.0683 mL
10 mM 0.2814 mL 1.4068 mL 2.8137 mL 7.0341 mL
15 mM 0.1876 mL 0.9379 mL 1.8758 mL 4.6894 mL
20 mM 0.1407 mL 0.7034 mL 1.4068 mL 3.5171 mL
25 mM 0.1125 mL 0.5627 mL 1.1255 mL 2.8137 mL
30 mM 0.0938 mL 0.4689 mL 0.9379 mL 2.3447 mL
40 mM 0.0703 mL 0.3517 mL 0.7034 mL 1.7585 mL
50 mM 0.0563 mL 0.2814 mL 0.5627 mL 1.4068 mL
60 mM 0.0469 mL 0.2345 mL 0.4689 mL 1.1724 mL
80 mM 0.0352 mL 0.1759 mL 0.3517 mL 0.8793 mL
100 mM 0.0281 mL 0.1407 mL 0.2814 mL 0.7034 mL
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Petadeferitrin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Petadeferitrin911714-45-9SP-420SP420SP 420FerroptosisInhibitorinhibitorinhibit

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상품명:
Petadeferitrin
Cat. No.:
HY-16912
수량:
MCE Japan Authorized Agent:

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