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CDK Related Products (488)
Related Products (488)
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Tanuxiciclib trihydrochloride
0 ImagesTanuxiciclib trihydrochloride is a cyclin dependent kinase (CDK) inhibitor.
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(S)-Ebvaciclib
0 ImagesSynonyms: (S)-PF-06873600(S)-PF-06873600 it the S enantiomer of PF-06873600. PF-06873600 is a selective and orally bioavailable inhibitor of cyclin-dependent kinase (CDK).
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Ceramide (Egg)
0 ImagesSynonyms: Ceramide (Egg, Chicken)Ceramide (Egg) (Ceramide (Egg, Chicken)) is a ceramide from chicken. Ceramide (Egg) is a sphingomyelin signaling pathway second messenger. Ceramide (Egg) activates PP2A, JNK, p38 MAPK, CAPK, ceramide-activated protein phosphatase, Vav, PKCζ, and SAPK/JNK cascade. Ceramide (Egg) downregulates or inhibits AKT, survivin, CDK2, mTOR, and FLIP. Ceramide (Egg) mediates apoptosis, autophagy, cell cycle arrest, mitochondrial dysfunction, redox state shifts, and ROS generation. Ceramide (Egg) can be used for the research of cancer and neurological disease.
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Abemaciclib metabolite M18-d8
0 ImagesCat. No.: HY-126534SPurity: 98.00%Synonyms: LSN3106729-d8Abemaciclib metabolite M18-d8 is the deuterium labeled Abemaciclib metabolite M18. Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 and a CRBN ligand have been used to design PROTAC CDK4/6 degrader.
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CDK/HDAC-IN-3
0 ImagesCDK/HDAC-IN-3 is an orally active HDACs/CDKs dual inhibitor. CDK/HDAC-IN-3 has potent and selective inhibition of CDK9, CDK12, CDK13, HDAC1, HDAC2 and HDAC3 with IC50 values of 98.32 nM, 98.85 nM, 100 nM, 62.12 nM, 93.28nM and 82.87 nM. CDK/HDAC-IN-3 can be used for the acute myeloid leukemia (AML) .
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NSC23005 sodium
0 ImagesNSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.
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Palbociclib monohydrochloride (Standard)
0 ImagesSynonyms: PD 0332991 monohydrochloride (Standard)Palbociclib (monohydrochloride) (Standard) is the analytical standard of Palbociclib (monohydrochloride). This product is intended for research and analytical applications. Palbociclib (PD 0332991) monohydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib monohydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.
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Atuveciclib S-Enantiomer
0 ImagesSynonyms: BAY-1143572 S-Enantiomer; (+)-Atuveciclib; (+)-BAY-1143572
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Cdc7-IN-5
0 ImagesCat. No.: HY-130517CAS No.: 1402057-86-6Cdc7-IN-5 (compound I-B) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-B. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle.
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CDC7 Human Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS02309CDC7 Human Pre-designed siRNA Set A contains three designed siRNAs for CDC7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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(S)-CDK2 degrader 6
0 Images(S)-CDK2 degrader 6 (Compound 8) is the S-enantiomer of CDK2 degrader 6 (HY-176444). (S)-CDK2 degrader 6 is a selective CDK2 molecular glue degrader with a DC50 of 166.7 nM in 24 h. (S)-CDK2 degrader 6 can be used for breast cancer research.
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