2944087-54-9
Chemical Structure
CDK/HDAC-IN-3
- CAS No.: 2944087-54-9
- Formula:C24H18Cl2N6O3
- Molecular Weight:509.34
IUPAC Name: N-(4-((2-aminophenyl)carbamoyl)phenyl)-4-(2,6-dichlorobenzamido)-1H-pyrazole-3-carboxamide
InChIKey: DMHUURDTAWQEKB-UHFFFAOYSA-N
SMILES: NC1=C(C=CC=C1)NC(C2=CC=C(C=C2)NC(C3=NNC=C3NC(C4=C(C=CC=C4Cl)Cl)=O)=O)=O
Biological Activity:
CDK/HDAC-IN-3 is an orally active HDACs/CDKs dual inhibitor. CDK/HDAC-IN-3 has potent and selective inhibition of CDK9, CDK12, CDK13, HDAC1, HDAC2 and HDAC3 with IC50 values of 98.32 nM, 98.85 nM, 100 nM, 62.12 nM, 93.28nM and 82.87 nM. CDK/HDAC-IN-3 can be used for the acute myeloid leukemia (AML) [1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
CDK/HDAC-IN-3 | 99.60% | CDK/HDAC-IN-3 is an orally active HDACs/CDKs dual inhibitor. CDK/HDAC-IN-3 has potent and selective inhibition of CDK9, CDK12, CDK13, HDAC1, HDAC2 and HDAC3 with IC50 values of 98.32 nM, 98.85 nM, 100 nM, 62.12 nM, 93.28nM and 82.87 nM. CDK/HDAC-IN-3 can be used for the acute myeloid leukemia (AML) . |
||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
