1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. CA Ⅱ Isoform
  5. CA Ⅱ Degrader

CA Ⅱ Degrader

CA Ⅱ Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-179467
    PROTAC hCAII degrader-1
    Degrader
    PROTAC hCAII degrader-1 is a potent PROTAC human carbonic anhydrase II (hCAII) degrader with an DC50 of 0.5 nM in HEK293 cells. PROTAC hCAII degrader-1 recruits cereblon (CRBN) E3 ubiquitin ligase to form a ternary complex. PROTAC hCAII degrader-1 enables ubiquitination and subsequent proteasomal degradation of hCAII.