2892306-56-6

PROTAC hCAII degrader-1 Chemical Structure
2892306-56-6

Chemical Structure

PROTAC hCAII degrader-1

  • CAS No.: 2892306-56-6
  • Formula:C32H41N5O7S
  • Molecular Weight:639.76

InChIKey: AZBRPAQQOMDJLZ-UHFFFAOYSA-N

SMILES: O=C(C1=CC=C(S(=O)(N)=O)C=C1)NCCCCCCCCCCCCNC2=CC=CC(C(N3C4C(NC(CC4)=O)=O)=O)=C2C3=O

Biological Activity: PROTAC hCAII degrader-1 is a potent PROTAC human carbonic anhydrase II (hCAII) degrader with an DC50 of 0.5 nM in HEK293 cells. PROTAC hCAII degrader-1 recruits cereblon (CRBN) E3 ubiquitin ligase to form a ternary complex. PROTAC hCAII degrader-1 enables ubiquitination and subsequent proteasomal degradation of hCAII[1].

Cat. No. Product Name Purity Description Pricing
HY-179467 		PROTAC hCAII degrader-1 PROTAC hCAII degrader-1 is a potent PROTAC human carbonic anhydrase II (hCAII) degrader with an DC50 of 0.5 nM in HEK293 cells. PROTAC hCAII degrader-1 recruits cereblon (CRBN) E3 ubiquitin ligase to form a ternary complex. PROTAC hCAII degrader-1 enables ubiquitination and subsequent proteasomal degradation of hCAII.
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