Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4709)
Related Products (4709)
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3-Acetylphenyl acetate
0 ImagesSynonyms: Tetramethyl thiol alcynic acid3-Acetylphenyl acetate (Tetramethyl thiol alcynic acid) can be used as pharmaceutical intermediates.
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Methyl 2-amino-5-bromobenzoate
0 ImagesMethyl 2-amino-5-bromobenzoate (Compound 8/12) is a pharmaceutical intermediate. Methyl 2-amino-5-bromobenzoate can be used to synthesize 2-benzamidobenzoic acid, a known FabH inhibitor. Derivatives of methyl 2-amino-5-bromobenzoate also inhibit PqsD, the pqs quorum sensing (QS) system, of Pseudomonas aeruginosa.
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2-Fluoro-4-iodobenzonitrile
0 Images2-Fluoro-4-iodobenzonitrile is a building block, which can be used to synthesize L. infantum trypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors. 2-Fluoro-4-iodo benzonitrile can also be used to synthesize transient receptor potential ankyrin 1 (TRPA1) antagonists.
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Alisporivir intermediate-1
0 ImagesAlisporivir intermediate-1 is an intermediate in the synthesis of Alisporivir. Alisporivir is used for the treatment of inflammatory and viral diseases.
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Chlorthalidone impurity
0 ImagesChlorthalidone impurity (Compound Impurity B) is an impurity of Chlorthalidone (HY-15833). Chlorthalidone is a type of thiazide-like diuretic and is used for the study of hypertension.
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Diethyl pyridine-2,4-dicarboxylate
0 ImagesDiethyl pyridine-2,4-dicarb is a potent prolyl 4-hydroxylase-directed proinhibitor. Diethyl pyridine-2,4-dicarb inhibits prolyl hydroxylation and procollagen processing in chick-embryo calvaria.
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1,4-Diphenylbuta-1,3-diyne
0 ImagesCat. No.: HY-W014785CAS No.: 886-66-81,4-Diphenylbuta-1,3-diyne (Compound 2a) is a synthetic symmetrical 1,3-diene derivative. 1,4-Diphenylbuta-1,3-diyne exhibits significant selective anti-proliferative activity against HeLa cells. 1,4-Diphenylbuta-1,3-diyne can be utilized in cervical cancer research.
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4H-Cyclopenta[2,1-b:3,4-b']dithiophene
![4H-Cyclopenta[2,1-b:3,4-b']dithiophene](https://file.medchemexpress.com/product_pic/hy-w004498.gif "Click to View 4H-Cyclopenta[2,1-b:3,4-b']dithiophene Product Detail")
0 ImagesCat. No.: HY-W004498CAS No.: 389-58-2Synonyms: 4H-Cyclopenta[1,2-b:5,4-b']dithiophene4H-Cyclopenta[2,1-b:3,4-b']dithiophene (4H-Cyclopenta[1,2-b:5,4-b']dithiophene) is a methylene-bridged fused-ring thiophene-based building block, which serves as a synthetic intermediate for organic photonic and electronic materials.
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H-Asn-Arg-OH diTFA
0 ImagesCat. No.: HY-131092APurity: 99.83%Synonyms: Asn-Arg diTFAH-Asn-Arg-OH diTFA is a dipeptide formed by the connection of asparagine and arginine via a peptide bond, which can be used in polypeptide synthesis.
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1,1'-Dibromoferrocene
0 Images1,1'-Dibromoferrocene is a drug synthesis intermediate that can be used to synthesize a wide number of 1,2-disubstituted ferrocenes.
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7-Aminodeacetoxycephalosporanic acid
0 ImagesSynonyms: 7-ADCA7-Aminodeacetoxycephalosporanic acid (7-ADCA) is a key intermediate in the synthesis of cephalosporins.
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Methoxy-PEG2000-C3-amide-C2-Mal
0 ImagesMethoxy-PEG2000-C3-amide-C2-Mal can bind to hemoglobin through the 93Cys residue to produce di-PEGylated hemoglobin.
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PTX-SS-COOH
0 ImagesCat. No.: HY-178078CAS No.: 1800077-28-4PTX-SS-COOH is the proform that can be grafted to the sulfhydryl modified gelatin to form the redox sensitive amphiphilic polymer. The nanoparticle (BSA/Gel-SS-PTX/PTX-SS-COOH NPs) demonstrates an excellent anticancer efficiency. PTX-SS-COOH can be applied in the research of targeted delivery for solid tumors (such as breast cancer and melanoma) by utilizing the unique characteristics of the tumor microenvironment (high GSH level).
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CCT-010354
0 ImagesCCT-010354 (Compound 63e) is an agent intermediate that can be used to synthesize PPARα/δ dual agonist.
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Phenylglyoxylic acid-d5
0 ImagesSynonyms: Benzoylformic acid-d5Phenylglyoxylic acid-d5 (Benzoylformic acid-d5) is a deuterium labeled Phenylglyoxylic acid (HY-W010255). Phenylglyoxylic acid (Benzoylformic acid) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid can be used as drug intermediate for synthesis of antineoplastic compounds.
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D-Lyxose
0 ImagesD-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose with significant potential for pharmaceutical synthesis. D-Lyxose serves as a starting material for antitumor agents (such as α-galactosylceramide-based immunostimulants). D-Lyxose acts as a precursor for L-nucleoside analogs used in the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars (such as L-ribose).
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5-Bromo-3-fluoropicolinic acid
0 ImagesCat. No.: HY-W005596CAS No.: 669066-91-5Synonyms: 5-Bromo-3-fluoropyridine-2-carboxylic acid5-Bromo-3-fluoropicolinic acid (5-Bromo-3-fluoropyridine-2-carboxylic acid) is a drug synthesis intermediate that can be used to synthesize an inhibitor of glycinamide ribonucleotide formyltransferase.
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Paliperidone impurity 15
0 ImagesCat. No.: HY-75261CAS No.: 84163-13-3Paliperidone impurity 15 is an impurity of Paliperidone.
