Chlorthalidone impurity
Based on 1 Customer Validation
Chlorthalidone impurity is a metabolite of Chlorthalidone (HY-15833). Chlorthalidone is a thiazide-like diuretic used to treat hypertension.
For research use only. We do not sell to patients.
- Purity: 99.68%
- CAS No.: 5270-74-6
- Formula: C14H10ClNO5S
- Molecular Weight:339.75
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 5270-74-6
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Appearance Solid
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Molecular Weight 339.75
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Formula C14H10ClNO5S
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Color White to off-white
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SMILES
O=C(O)C1=CC=CC=C1C(C2=CC=C(Cl)C(S(=O)(N)=O)=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (367.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Bauer J, et al. Stability-indicating assay for chlorthalidone formulation: evaluation of the USP analysis and a high-performance liquid chromatographic analysis. J Pharm Sci. 1983 Aug;72(8):924-8. [Content Brief]
[2]. Barrios V, et al. Which thiazide to choose as add-on therapy for hypertension? Integr Blood Press Control. 2014 Jul 30;7:35-47. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9433 mL | 14.7167 mL | 29.4334 mL | 73.5835 mL |
| 5 mM | 0.5887 mL | 2.9433 mL | 5.8867 mL | 14.7167 mL | |
| 10 mM | 0.2943 mL | 1.4717 mL | 2.9433 mL | 7.3584 mL | |
| 15 mM | 0.1962 mL | 0.9811 mL | 1.9622 mL | 4.9056 mL | |
| 20 mM | 0.1472 mL | 0.7358 mL | 1.4717 mL | 3.6792 mL | |
| 25 mM | 0.1177 mL | 0.5887 mL | 1.1773 mL | 2.9433 mL | |
| 30 mM | 0.0981 mL | 0.4906 mL | 0.9811 mL | 2.4528 mL | |
| 40 mM | 0.0736 mL | 0.3679 mL | 0.7358 mL | 1.8396 mL | |
| 50 mM | 0.0589 mL | 0.2943 mL | 0.5887 mL | 1.4717 mL | |
| 60 mM | 0.0491 mL | 0.2453 mL | 0.4906 mL | 1.2264 mL | |
| 80 mM | 0.0368 mL | 0.1840 mL | 0.3679 mL | 0.9198 mL | |
| 100 mM | 0.0294 mL | 0.1472 mL | 0.2943 mL | 0.7358 mL |
Chlorthalidone impurity Related Classifications
HY-43670 Related Classifications
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