7-Aminodeacetoxycephalosporanic acid
Based on 1 Customer Validation
7-Aminodeacetoxycephalosporanic acid (7-ADCA) is a key intermediate in the synthesis of cephalosporins.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 22252-43-3
- Formula: C8H10N2O3S
- Molecular Weight:214.25
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Key intermediates in the synthesis of cephalosporins are 7-Aminocephalosporanic acid (HY-B1434) and 7-Aminodesacetoxycephalosporanic acid (7-ADCA). 7-Aminodesacetoxycephalosporanic acid (7-ADCA) is produced from Penicillin G (HY-N7139) by Penicillium chrysogenum by a process that comprises several polluting chemical steps, followed by enzymatic deacylation by using penicillin acylase[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 22252-43-3
-
Appearance Solid
-
Molecular Weight 214.25
-
Formula C8H10N2O3S
-
Color Light yellow to yellow
-
SMILES
O=C1N2[C@]([C@@H]1N)([H])SCC(C)=C2C(O)=O
-
Synonyms
7-ADCA
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
NH4OH : 50 mg/mL (233.38 mM; ultrasonic and adjust pH to 9 with NH4OH)
25 % w/v ammonia solution : 50 mg/mL (233.38 mM; ultrasonic and adjust pH to 9 with NH4OH)
H2O : 41.67 mg/mL (194.50 mM; ultrasonic and adjust pH to 10 with NaOH)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (275 KB)
-
SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / NH4OH / 25 % w/v ammonia solution | 1 mM | 4.6675 mL | 23.3377 mL | 46.6753 mL | 116.6883 mL |
| 5 mM | 0.9335 mL | 4.6675 mL | 9.3351 mL | 23.3377 mL | |
| 10 mM | 0.4668 mL | 2.3338 mL | 4.6675 mL | 11.6688 mL | |
| 15 mM | 0.3112 mL | 1.5558 mL | 3.1117 mL | 7.7792 mL | |
| 20 mM | 0.2334 mL | 1.1669 mL | 2.3338 mL | 5.8344 mL | |
| 25 mM | 0.1867 mL | 0.9335 mL | 1.8670 mL | 4.6675 mL | |
| 30 mM | 0.1556 mL | 0.7779 mL | 1.5558 mL | 3.8896 mL | |
| 40 mM | 0.1167 mL | 0.5834 mL | 1.1669 mL | 2.9172 mL | |
| 50 mM | 0.0934 mL | 0.4668 mL | 0.9335 mL | 2.3338 mL | |
| 60 mM | 0.0778 mL | 0.3890 mL | 0.7779 mL | 1.9448 mL | |
| 80 mM | 0.0583 mL | 0.2917 mL | 0.5834 mL | 1.4586 mL | |
| 100 mM | 0.0467 mL | 0.2334 mL | 0.4668 mL | 1.1669 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
7-Aminodeacetoxycephalosporanic acid Related Classifications
HY-W014217 Related Classifications
Powered by Bioz