HIF/HIF Prolyl-Hydroxylase Modulator
-
THS-044
0 ImagesTHS-044 is a modulator of the formation of the HIF2α/ARNT heterodimer. THS-044 binding stabilizes the HIF2α PAS-B folded state (KD = 2 μM), for regulating HIF2 activity in endogenous and pathological settings, and does not bind to HIF1α or ARNT PAS-B. THS-044 can be used for the study of diseases related to hypoxia.
-
Acetylarenobufagin
0 ImagesAcetylarenobufagin is a steroidal hypoxia inducible factor-1 (HIF-I) modulator.
