62054-67-5

THS-044 Chemical Structure
62054-67-5

Chemical Structure

THS-044

  • CAS No.: 62054-67-5
  • Formula:C11H12F3N3O3
  • Molecular Weight:291.23

IUPAC Name: N-(2-nitro-4-(trifluoromethyl)phenyl)morpholin-4-amine

InChIKey: XUPDNGHJBHPAKD-UHFFFAOYSA-N

SMILES: FC(C1=CC=C(NN2CCOCC2)C([N+]([O-])=O)=C1)(F)F

Biological Activity: THS-044 is a modulator of the formation of the HIF2α/ARNT heterodimer. THS-044 binding stabilizes the HIF2α PAS-B folded state (KD = 2 μM), for regulating HIF2 activity in endogenous and pathological settings, and does not bind to HIF1α or ARNT PAS-B. THS-044 can be used for the study of diseases related to hypoxia[1].

Cat. No. Product Name Purity Description Pricing
HY-19621 		THS-044 99.37% THS-044 is a modulator of the formation of the HIF2α/ARNT heterodimer. THS-044 binding stabilizes the HIF2α PAS-B folded state (KD = 2 μM), for regulating HIF2 activity in endogenous and pathological settings, and does not bind to HIF1α or ARNT PAS-B. THS-044 can be used for the study of diseases related to hypoxia.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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