Nitisinone-13C6
Nitisinone-13C6 is a 13C-labeled Nitisinone (HY-B0607). Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism.
For research use only. We do not sell to patients.
- CAS No.: 1246815-63-3
- Formula: C813C6H10F3NO5
- Molecular Weight:335.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1246815-63-3
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Unlabeled Cas 104206-65-7
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Molecular Weight 335.18
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Formula C813C6H10F3NO5
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SMILES
O=C([13CH]1[13C]([13CH2][13CH2][13CH2][13C]1=O)=O)C2=C(C=C(C=C2)C(F)(F)F)[N+]([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nitisinone-13C6 Related Classifications
HY-W777526 Related Classifications
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