Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2504)
Related Products (2504)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Antiparasitic agent-39
0 ImagesCat. No.: HY-180943CAS No.: 2568585-37-3Antiparasitic agent-39 (Compound 14) is a selective antiparasitic agent and Deferasirox (HY-17359) derivative. Antiparasitic agent-39 reduces the mitochondrial membrane potential. Antiparasitic agent-39 shows antiparasitic activity against T. brucei, T. gambiense, L. Mexicana, T. gondii, B. divergens, P. falciparum with EC50s of 4.2 nM, 10.4 nM, 52.0 nM, 17.0 nM, 41.2 nM, 54.8 nM, respectively.
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Panidazole (Standard)
0 ImagesCat. No.: HY-101715RCAS No.: 13752-33-5Panidazole (Standard) is the analytical standard of Panidazole (HY-101715). This product is intended for research and analytical applications. Panidazole is an amoebicide.
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Bephenium (hydroxynaphthoate) (Standard)
0 ImagesBephenium (hydroxynaphthoate) (Standard) is the analytical standard of Bephenium (hydroxynaphthoate). This product is intended for research and analytical applications.
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AN11736
0 ImagesCat. No.: HY-112905CAS No.: 2152662-85-4AN11736 is a CPSF3 inhibitor. AN11736 exerts a potent anti-trypsin effect by specifically inhibiting the activity of the trypanosome CPSF3 endonuclease, disrupting the mRNA maturation process. AN11736 exhibits IC50s against T. congolense and T. vivax of 0.14 and 1.3 nM, respectively. AN11736 exhibits strong anti-trypsin activity in mouse and cattle models.
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Amythiamicin C
0 ImagesCat. No.: HY-N13881CAS No.: 156620-47-2Amythiamicin C is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum.
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Amotosalen hydrochloride (Standard)
0 ImagesCat. No.: HY-107004ARCAS No.: 161262-45-9Synonyms: S-59 (Standard)Amotosalen hydrochloride (Standard) (S-59 (Standard)) is the analytical standard of Amotosalen (hydrochloride) (HY-107004A). This product is intended for research and analytical applications. Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinKing psoralen compound, which is used to neutralise pathogens. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells. Amotosalen can be used for the study of blood system pathogen reduction technology and graft-versus-host disease (GVHD).
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RH01201
0 ImagesCat. No.: HY-173028CAS No.: 300664-41-9RH01201 is the non-competitive inhibitor for plasmepsin II with a Ki of 123 μM.
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AB 3217-B
0 ImagesCat. No.: HY-117241CAS No.: 139159-00-5AB 3217-B is an analog of AB 3217-A and has anti-mite activity.
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Quassin (Standard)
0 ImagesQuassin (Standard) is the analytical standard of Quassin. This product is intended for research and analytical applications. Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity.
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Teclozan (Standard)
0 ImagesTeclozan (Standard) is the analytical standard of Teclozan. This product is intended for research and analytical applications. Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti-G. intestinalis. Teclozan can be used for the research of protozoan infections.
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Anti-Trypanosoma cruzi agent-5
0 ImagesCat. No.: HY-116004CAS No.: 205381-53-9Anti-Trypanosoma cruzi agent-5 (compoung 8) is a potent inhibitor of Trypanosoma cruzi proliferation.
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SDH-IN-43
0 ImagesCat. No.: HY-W677714CAS No.: 163105-64-4SDH-IN-43 (Compound i-19) is a succinate dehydrogenase (SDH) inhibitor. SDH-IN-43 shows potent inhibitory activity against caenorhabditis elegans wirh an IC50 of 6.67 μM. SDH-IN-43 can significantly reduce caenorhabditis elegans reproductive ability and movement ability, and is also effective against drug-resistant strains of Levamisole (HY-A0106), Benzimidazole (HY-Y1825), and Ivermectin (HY-15310). SDH-IN-43 can be used for the research of parasite infection.
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Demiditraz
0 ImagesCat. No.: HY-14787CAS No.: 944263-65-4Synonyms: PF 3814927Demiditraz (PF 3814927) (example 58) is a potent parasiticide. Demiditraz shows potent anti-tick activity against Rhipicephalus sanguineus with an ED100 of 0.1 mg/cm2. Demiditraz can be used for preventing the transmission of tick-borne diseases.
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Oltipraz (Standard)
0 ImagesSynonyms: RP 35972 (Standard); NSC 347901 (Standard)Oltipraz (Standard) is the analytical standard of Oltipraz. This product is intended for research and analytical applications. Oltipraz has an inhibitory effect on HIF-1α activation in a time-dependent manner, completely abrogating HIF-1α induction at ≥10 μM concentrations, the IC50 of Oltipraz for HIF-1α inhibition is 10 μM. Oltipraz is a potent Nrf2 activator.
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Cephaibol B
0 ImagesCat. No.: HY-N5176CAS No.: 304911-39-5
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S-WJM992
0 ImagesCat. No.: HY-159603S-WJM992 (compound 10ahb) is an antiparasitic agent that inhibits ATPase activity under high [Na+] conditions. S-WJM992 also has significant inhibitory effects on parasites that have developed PfATP4 inhibitor-resistance. S-WJM992 is a potential transmission blocker that effectively inhibits gamete development and prevents parasite transmission to mosquitoes via blood feeding.
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Fenitrothion (Standard)
0 ImagesFenitrothion (Standard) is the analytical standard of Fenitrothion (HY-B1885). This product is intended for research and analytical applications. Fenitrothion is a broad-spectrum and orally active insecticide/acaricide. Fenitrothion inhibits cholinesterase, AMPKα and IRS1/PI3K/AKT. Fenitrothion causes Apoptosis, reduces SOD activity. Fenitrothion shows insecticidal effect against Rhyzopertha dominica and Tribolium castaneum adults. Fenitrothion is widely used in cotton crops, vegetable crops, fruit crops and field crops, especially rice. Fenitrothion can be used for brain and spleen toxicology studies.
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Insecticidal agent 7
0 ImagesCat. No.: HY-163157CAS No.: 2951079-77-7Insecticidal agent 7 (Compound 21m) is an insecticide that targets the insect ryanodine receptors (RyRs) with a LC50 of 0.0937 mg/L for the Plutella xylostella. Insecticidal agent 7 (Compound 21m) exhibits good selectivity and low toxicity towards non-target organisms.
