Amotosalen hydrochloride (Standard)
Amotosalen hydrochloride (Standard) (S-59 (Standard)) is the analytical standard of Amotosalen (hydrochloride) (HY-107004A). This product is intended for research and analytical applications. Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinKing psoralen compound, which is used to neutralise pathogens. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells. Amotosalen can be used for the study of blood system pathogen reduction technology and graft-versus-host disease (GVHD).
For research use only. We do not sell to patients.
- CAS No.: 161262-45-9
- Formula: C17H20ClNO4
- Molecular Weight:337.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 161262-45-9
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Molecular Weight 337.80
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Formula C17H20ClNO4
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SMILES
NCCOCC(C1=CC(C(C)=C2)=C3OC2=O)=C(OC1=C3C)C.[H]Cl
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Synonyms
S-59 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Amotosalen: Allogeneic Cellular Immunotherapies system, INTERCEPT Plasma System, INTERCEPT Platelet System, S 59. BioDrugs. 2003;17(1):66-8. [Content Brief]
[2]. Lanteri MC, et al. Inactivation of a broad spectrum of viruses and parasites by photochemical treatment of plasma and platelets using amotosalen and ultraviolet A light. Transfusion. 2020 Jun;60(6):1319-1331. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)