64224-21-1
64224-21-1
Chemical Structure
Oltipraz
Synonym(s): RP 35972; NSC 347901
- CAS No.: 64224-21-1
- Formula:C8H6N2S3
- Molecular Weight:226.34
IUPAC Name: 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione
InChIKey: CKNAQFVBEHDJQV-UHFFFAOYSA-N
SMILES: S=C1SSC(C2=NC=CN=C2)=C1C
Biological Activity: Oltipraz has an inhibitory effect on HIF-1α activation in a time-dependent manner, completely abrogating HIF-1α induction at ≥10 μM concentrations, the IC50 of Oltipraz for HIF-1α inhibition is 10 μM. Oltipraz is a potent Nrf2 activator.
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Oltipraz | 99.87% | Oltipraz has an inhibitory effect on HIF-1α activation in a time-dependent manner, completely abrogating HIF-1α induction at ≥10 μM concentrations, the IC50 of Oltipraz for HIF-1α inhibition is 10 μM. Oltipraz is a potent Nrf2 activator. | ||||||||||||||||||||
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Oltipraz (Standard) | ≥98% | Oltipraz (Standard) is the analytical standard of Oltipraz. This product is intended for research and analytical applications. Oltipraz has an inhibitory effect on HIF-1α activation in a time-dependent manner, completely abrogating HIF-1α induction at ≥10 μM concentrations, the IC50 of Oltipraz for HIF-1α inhibition is 10 μM. Oltipraz is a potent Nrf2 activator. | ||||||||||||||||||||
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Oltipraz (GMP) | Oltipraz (GMP) is Oltipraz (HY-12519) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Oltipraz has an inhibitory effect on HIF-1α activation. Oltipraz is a potent Nrf2 activator. | |||||||||||||||||||||
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Oltipraz-d3 | Oltipraz-d3 is the deuterium labeled Oltipraz. Oltipraz has an inhibitory effect on HIF-1α activation in a time-dependent manner, completely abrogating HIF-1α induction at ≥10 μM concentrations, the IC50 of Oltipraz for HIF-1α inhibition is 10 μM. Oltipraz is a potent Nrf2 activator. | |||||||||||||||||||||
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