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Cat. No.: HY-116004

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Anti-Trypanosoma cruzi agent-5

Anti-Trypanosoma cruzi agent-5 (compoung 8) is a potent inhibitor of Trypanosoma cruzi proliferation.

For research use only. We do not sell to patients.

CAS No.: 205381-53-9
Formula: C₁₅H₁₃NO₂S
Molecular Weight:271.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Anti-Trypanosoma cruzi agent-5 Chemical Structure

CAS No.: 205381-53-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Anti-Trypanosoma cruzi agent-5 (compoung 8) is a potent inhibitor of Trypanosoma cruzi proliferation^[1].

All Parasite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HFF	IC₅₀	2.8 μM Compound: 1 (wc-9)	Antiparasitic activity against Toxoplasma gondii tachyzoites m2m3 infected HFF cells Antiparasitic activity against Toxoplasma gondii tachyzoites m2m3 infected HFF cells	[PMID: 17643987]
Vero	ED₅₀	>50 μM Compound: 1, WC-9	Cytotoxicity against african green monkey Vero cells by Alamar blue assay Cytotoxicity against african green monkey Vero cells by Alamar blue assay	[PMID: 24090919]
Vero	ED₅₀	82.6 μM Compound: 1; WC-9	Cytotoxicity against African green monkey Vero cells after 3 to 4 days by Alamar Blue dye-based spectrophotometric method Cytotoxicity against African green monkey Vero cells after 3 to 4 days by Alamar Blue dye-based spectrophotometric method	[PMID: 29107437]
Vero	ED₅₀	82.6 μM Compound: 37; WC-9	Cytotoxicity against African green monkey Vero cells assessed as cell growth inhibition by alamar blue assay Cytotoxicity against African green monkey Vero cells assessed as cell growth inhibition by alamar blue assay	[PMID: 34894691]

Chemical Information

CAS No. 205381-53-9
Molecular Weight 271.33
Formula C₁₅H₁₃NO₂S
SMILES

N#CSCCOC1=CC=C(C=C1)OC2=CC=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Szajnman SH, et, al. Design and synthesis of aryloxyethyl thiocyanate derivatives as potent inhibitors of Trypanosoma cruzi proliferation. J Med Chem. 2000 May 4;43(9):1826-40. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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