2. Signaling Pathways
  3. Neuronal Signaling
  4. Sigma Receptor
  5. Sigma 2 Receptor Isoform
  6. Sigma 2 Receptor Activator

Sigma 2 Receptor Activator

Sigma 2 Receptor Activators (2):

Cat. No. Product Name Effect Purity
  • HY-117420
    CM764
    		Activator
    CM764 is an activator for sigma receptor with Ki of 86.6 and 3.5 nM for sigma-1 receptor and sigma-2 receptor. CM764 increases cytoplasmic calcium, NAD+/NADH, and ATP levels, and decreases the concentration of ROS.
  • HY-N15339A
    Convolamine hydrochloride
    		Activator
    Convolamine hydrochloride is a tropane alkaloid and a potent Sigma-1 receptor positive allosteric modulator with an IC50 value of 289 nM. Convolamine hydrochloride can be extracted from Convolvulus plauricalis. Convolamine hydrochloride exhibits cognitive-improving and neuroprotective properties. Convolamine hydrochloride can be used in research related to Wolfram syndrome and Alzheimer's disease.