500-56-1
500-56-1
Chemical Structure
Convolamine
- CAS No.: 500-56-1
- Formula:C17H23NO4
- Molecular Weight:305.37
InChIKey: AEFPCFUCFQBXDQ-WDNDVIMCSA-N
SMILES: O=C(C(C=C1)=CC(OC)=C1OC)O[C@H](C[C@]2([H])CC3)C[C@]3([H])N2C
Biological Activity: Convolamine is an alkaloid found in Convolvulus pluricaulis and an effective positive modulator of the sigma-1 receptor (IC50 = 289 nM), exhibiting cognitive and neuroprotective properties[1][2].
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Convolamine | 99.89% | Convolamine is an alkaloid found in Convolvulus pluricaulis and an effective positive modulator of the sigma-1 receptor (IC50 = 289 nM), exhibiting cognitive and neuroprotective properties. | ||||||||||||||||||||
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References
- [1]. Gapparov A M, et al. Alkaloids of Convolvulus subhirsutus from Uzbekistan[J]. Chemistry of Natural Compounds, 2007, 43: 291-292.
- [2]. Crouzier L, et al. Convolamine, a tropane alkaloid extracted from Convolvulus plauricalis, is a potent sigma‐1 receptor‐positive modulator with cognitive and neuroprotective properties[J]. Phytotherapy Research, 2024, 38(2): 694-712.
Keywords
