2. Signaling Pathways
  3. Anti-infection
  4. Hepatitis E Virus (HEV)
  5. Hepatitis E Virus (HEV) Inhibitor

Hepatitis E Virus (HEV) Inhibitor

Hepatitis E Virus (HEV) Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-178137
    SCR007
    		Inhibitor
    SCR007 is a synthetic carbohydrate receptor (SCR) with broad-spectrum antiviral activity. SCR007 inhibits the entry of enveloped viruses across multiple families (Coronaviridae: SARS-CoV-1, SARS-CoV-2, MERS-CoV; Filoviridae: EBOV, MARV; Paramyxoviridae: NiV, HeV) and the glycosylated nonenveloped rotavirus. SCR007 binds viral envelope N-glycans, blocking viral binding to host cells or both binding and membrane fusion. SCR007 exerts prophylactic effects in hACE2 mice infected with SARS-CoV-2. SCR007 can be used for the study and prevention of enveloped virus pandemics.
  • HY-178135
    SCR005
    		Inhibitor
    SCR005 is a synthetic carbohydrate receptor (SCR) with broad-spectrum antiviral activity. SCR005 inhibits the entry of enveloped viruses across multiple families (Coronaviridae: SARS-CoV-1, SARS-CoV-2, MERS-CoV; Filoviridae: EBOV, MARV; Paramyxoviridae: NiV, HeV) and the glycosylated nonenveloped rotavirus. SCR005 binds viral envelope N-glycans, blocking viral binding to host cells or both binding and membrane fusion. SCR005 exerts prophylactic effects in hACE2 mice infected with SARS-CoV-2. SCR005 can be used for the study and prevention of enveloped virus pandemics.
  • HY-181032
    Antiviral agent 77
    		Inhibitor
    Antiviral agent 77 (Compound 46) is a potent, orally active, blood-brain-barrier permeable antiviral agent. Antiviral agent 77 shows antiviral activity against CedV (EC50: 1.08 μM in the rCedV-Luc reporter assay), NiV-M (EC50: 2.91 μM), NiV-B and HeV.